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← Older revision		Revision as of 03:35, 13 February 2025
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	~~'''~~Wogonin~~''' is a flavonoid, a type of chemical compound, that is found in the roots of the plant ''Scutellaria baicalensis''. It has been studied for its potential anti-inflammatory and anti-cancer effects.~~		{{DISPLAYTITLE:Wogonin}}

	==~~Chemical Structure~~==		== Overview ==
	Wogonin is a flavone, a type of flavonoid, which is ~~a class~~ of ~~secondary~~ plant ~~metabolites. Its chemical formula is C16H12O5 and its molecular weight is 284.26 g/mol~~. It is ~~a yellow crystalline powder at room temperature~~.		[[File:Wogonin.svg\|thumb\|right\|Chemical structure of Wogonin]]
			'''Wogonin''' is a naturally occurring [[flavone]], a type of [[flavonoid]], which is found in the root of the plant [[Scutellaria baicalensis]], commonly known as [[Baikal skullcap]]. It is one of the major active components of this traditional Chinese medicinal herb.

	==~~Sources~~==		== Chemical Properties ==
	Wogonin is ~~found in the roots of the plant ''Scutellaria baicalensis''~~, ~~also known as Chinese skullcap or Baikal skullcap. This plant~~ is a ~~species~~ of ~~flowering plant in the mint family, Lamiaceae~~, and is ~~native to several countries in East Asia~~.		Wogonin is characterized by its chemical structure as a flavone, which is a class of [[polyphenolic]] compounds. The molecular formula of wogonin is C16H12O5, and it is known for its distinctive yellow crystalline appearance.

	==~~Potential Health Benefits~~==		== Biological Activity ==
	Wogonin has been studied for its potential ~~health benefits~~, ~~particularly its~~ anti-inflammatory ~~and anti-cancer effects. Some studies have suggested that wogonin may inhibit the growth of certain types of cancer cells~~, ~~including breast cancer~~ and ~~leukemia cells~~. ~~However, more research is needed~~ to ~~confirm these findings~~ and ~~to understand how wogonin works in the body~~.		Wogonin has been studied for its potential [[pharmacological]] effects. It exhibits a range of biological activities, including [[anti-inflammatory]], [[antioxidant]], and [[anticancer]] properties. These effects are attributed to its ability to modulate various [[cell signaling pathways]] and [[gene expression]].

	==~~Safety and Side~~ Effects==		=== Anti-inflammatory Effects ===
	~~As with any supplement~~, ~~it's important to talk to your doctor before starting to take wogonin~~. ~~While it's generally considered safe,~~ it ~~can interact with other medications and may have side effects, especially at high doses~~.		Wogonin has been shown to inhibit the production of [[pro-inflammatory cytokines]] and reduce the activity of [[nuclear factor kappa B]] (NF-_B), a key regulator of the inflammatory response. This makes it a compound of interest in the treatment of inflammatory diseases.

	==~~See Also~~==		=== Antioxidant Properties ===
			As an antioxidant, wogonin helps in scavenging [[free radicals]] and reducing oxidative stress in cells. This property is beneficial in protecting cells from damage and in the prevention of [[chronic diseases]] associated with oxidative stress.

			=== Anticancer Potential ===
			Research has indicated that wogonin may induce [[apoptosis]] in various [[cancer cell lines]], including those of [[breast cancer]], [[prostate cancer]], and [[leukemia]]. It is thought to exert these effects by influencing [[cell cycle arrest]] and promoting [[programmed cell death]].

			== Pharmacokinetics ==
			The absorption, distribution, metabolism, and excretion of wogonin have been studied to understand its [[bioavailability]] and therapeutic potential. Wogonin is metabolized primarily in the liver and excreted through the kidneys.

			== Traditional and Modern Uses ==
			In traditional Chinese medicine, wogonin-containing herbs like Scutellaria baicalensis have been used for centuries to treat conditions such as [[fever]], [[hepatitis]], and [[allergies]]. Modern research continues to explore its potential applications in [[pharmacotherapy]].

			== Safety and Toxicity ==
			Studies on the safety profile of wogonin suggest that it is generally well-tolerated at therapeutic doses. However, further research is needed to fully understand its long-term effects and potential interactions with other medications.

			== Related Pages ==
	* [[Flavonoid]]		* [[Flavonoid]]
	* [[Scutellaria baicalensis]]		* [[Scutellaria baicalensis]]
			* [[Antioxidant]]
	* [[Anti-inflammatory]]		* [[Anti-inflammatory]]
	* [[~~Anti-cancer~~]]		* [[Cancer treatment]]

	[[Category:Flavonoids]]		[[Category:Flavonoids]]
	[[Category:Phytochemicals]]		[[Category:Phytochemicals]]
	[[Category:~~Medicinal plants~~]]		[[Category:Traditional Chinese medicine]]

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2024-02-25T21:49:35Z

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'''Wogonin''' is a flavonoid, a type of chemical compound, that is found in the roots of the plant ''Scutellaria baicalensis''. It has been studied for its potential anti-inflammatory and anti-cancer effects.

==Chemical Structure==
Wogonin is a flavone, a type of flavonoid, which is a class of secondary plant metabolites. Its chemical formula is C16H12O5 and its molecular weight is 284.26 g/mol. It is a yellow crystalline powder at room temperature.

==Sources==
Wogonin is found in the roots of the plant ''Scutellaria baicalensis'', also known as Chinese skullcap or Baikal skullcap. This plant is a species of flowering plant in the mint family, Lamiaceae, and is native to several countries in East Asia.

==Potential Health Benefits==
Wogonin has been studied for its potential health benefits, particularly its anti-inflammatory and anti-cancer effects. Some studies have suggested that wogonin may inhibit the growth of certain types of cancer cells, including breast cancer and leukemia cells. However, more research is needed to confirm these findings and to understand how wogonin works in the body.

==Safety and Side Effects==
As with any supplement, it's important to talk to your doctor before starting to take wogonin. While it's generally considered safe, it can interact with other medications and may have side effects, especially at high doses.

==See Also==
* [[Flavonoid]]
* [[Scutellaria baicalensis]]
* [[Anti-inflammatory]]
* [[Anti-cancer]]

[[Category:Flavonoids]]
[[Category:Phytochemicals]]
[[Category:Medicinal plants]]

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Wogonin - Revision history

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