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	'''~~Wakefulness~~-promoting agent'''~~‏‎, also known as [[eugeroic]],~~ is a type of [[~~pharmaceutical~~ drug]] that is used to ~~treat~~ [[~~sleep disorders~~]] such as [[narcolepsy]], [[sleep ~~apnea~~]], and [[~~shift work~~ sleep ~~disorder~~]]. ~~These agents work by stimulating the~~ [[~~central nervous system]] to increase [[alertness~~]] and ~~[[wakefulness]]~~.		{{DISPLAYTITLE:Wakefulness-promoting agent}}

			== Wakefulness-promoting agent ==

			[[File:Modafinil.svg\|thumb\|right\|Chemical structure of Modafinil, a common wakefulness-promoting agent.]]

			A '''wakefulness-promoting agent''' is a type of [[drug]] that is used to enhance [[alertness]] and [[wakefulness]] in individuals. These agents are often prescribed to treat conditions such as [[narcolepsy]], [[shift work sleep disorder]], and [[obstructive sleep apnea]]. They are distinct from traditional [[stimulants]] in that they generally have a lower potential for abuse and fewer side effects.

	== Mechanism of Action ==		== Mechanism of Action ==

	Wakefulness-promoting agents work by ~~interacting with the~~ [[neurotransmitter]] systems in the brain. ~~They increase~~ the ~~release of~~ [[dopamine]], ~~a neurotransmitter that plays a key role in regulating sleep and~~ wakefulness~~. Some~~ agents ~~also inhibit~~ the ~~reuptake~~ of ~~dopamine~~, thereby ~~increasing its availability in the brain~~.		Wakefulness-promoting agents work by affecting various [[neurotransmitter]] systems in the [[brain]]. The exact mechanism of action can vary between different agents, but they often involve modulation of the [[dopamine]] and [[norepinephrine]] pathways. For example, [[modafinil]], one of the most well-known wakefulness-promoting agents, is believed to increase the availability of these neurotransmitters, thereby enhancing wakefulness and alertness.

	== ~~Types of~~ Wakefulness-~~Promoting~~ Agents ==		== Common Wakefulness-promoting Agents ==

	~~There are several types of~~ wakefulness-promoting ~~agents~~, ~~including:~~		* '''[[Modafinil]]''': Modafinil is a widely used wakefulness-promoting agent that is prescribed for narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It is known for its relatively mild side effect profile compared to traditional stimulants.

	* [[~~Modafinil~~]]: ~~This~~ is a ~~popular wakefulness-promoting agent that~~ is used ~~to treat narcolepsy and other sleep disorders~~. It ~~works by increasing~~ the ~~release~~ of ~~dopamine in the brain~~.		* '''[[Armodafinil]]''': Armodafinil is a derivative of modafinil and is used for similar indications. It is the R-enantiomer of modafinil and is thought to have a longer duration of action.

	* [[Armodafinil]]: This is a more potent version of modafinil. It has a longer half-life, which means it stays in the body for a longer period of time.		== Clinical Uses ==

	* [[~~Methylphenidate~~]]~~: This is a stimulant drug that is commonly used to treat [[Attention Deficit Hyperactivity Disorder~~ (ADHD)]]~~‏‎. It works by increasing the release of dopamine and norepinephrine in the brain~~.		Wakefulness-promoting agents are primarily used in the treatment of sleep disorders. They are prescribed to help patients maintain wakefulness during the day and improve their overall quality of life. In addition to their use in sleep disorders, these agents are sometimes used off-label for conditions such as [[attention deficit hyperactivity disorder]] (ADHD) and [[depression]], although such uses should be approached with caution.

	== Side Effects ==		== Side Effects ==

	~~Like all drugs,~~ wakefulness-promoting agents can ~~have~~ side effects. ~~These can~~ include ~~[[insomnia]],~~ [[headache]], [[nausea]], [[~~anxiety~~]], and [[~~hypertension~~]]. ~~In rare cases, these drugs can cause~~ serious side effects ~~such as~~ [[~~psychosis~~]] or [[~~cardiovascular disease~~]].		While wakefulness-promoting agents are generally well-tolerated, they can cause side effects in some individuals. Common side effects include [[headache]], [[nausea]], [[nervousness]], and [[insomnia]]. More serious side effects are rare but can include [[allergic reactions]] and [[psychiatric symptoms]].

	== ~~See Also~~ ==		== Related pages ==

	* [[Stimulant]]		* [[Stimulant]]
	* [[~~Nootropic~~]]		* [[Narcolepsy]]
	* [[Sleep disorder]]		* [[Sleep disorder]]
	* [[~~Neurotransmitter~~]]		* [[Attention deficit hyperactivity disorder]]

	[[Category:Pharmacology]]		[[Category:Pharmacology]]
	[[Category:Sleep disorders]]		[[Category:Sleep disorders]]
	~~[[Category:Neurology]]~~
	~~{{Pharma-stub}}~~
	~~{{Medicine-stub}}~~

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'''Wakefulness-promoting agent'''‏‎, also known as [[eugeroic]], is a type of [[pharmaceutical drug]] that is used to treat [[sleep disorders]] such as [[narcolepsy]], [[sleep apnea]], and [[shift work sleep disorder]]. These agents work by stimulating the [[central nervous system]] to increase [[alertness]] and [[wakefulness]].

== Mechanism of Action ==

Wakefulness-promoting agents work by interacting with the [[neurotransmitter]] systems in the brain. They increase the release of [[dopamine]], a neurotransmitter that plays a key role in regulating sleep and wakefulness. Some agents also inhibit the reuptake of dopamine, thereby increasing its availability in the brain.

== Types of Wakefulness-Promoting Agents ==

There are several types of wakefulness-promoting agents, including:

* [[Modafinil]]: This is a popular wakefulness-promoting agent that is used to treat narcolepsy and other sleep disorders. It works by increasing the release of dopamine in the brain.

* [[Armodafinil]]: This is a more potent version of modafinil. It has a longer half-life, which means it stays in the body for a longer period of time.

* [[Methylphenidate]]: This is a stimulant drug that is commonly used to treat [[Attention Deficit Hyperactivity Disorder (ADHD)]]‏‎. It works by increasing the release of dopamine and norepinephrine in the brain.

== Side Effects ==

Like all drugs, wakefulness-promoting agents can have side effects. These can include [[insomnia]], [[headache]], [[nausea]], [[anxiety]], and [[hypertension]]. In rare cases, these drugs can cause serious side effects such as [[psychosis]] or [[cardiovascular disease]].

== See Also ==

* [[Stimulant]]
* [[Nootropic]]
* [[Sleep disorder]]
* [[Neurotransmitter]]

[[Category:Pharmacology]]
[[Category:Sleep disorders]]
[[Category:Neurology]]
{{Pharma-stub}}
{{Medicine-stub}}

Wakefulness-promoting agent - Revision history

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