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	<title>Virulence - Revision history</title>
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	<updated>2026-04-25T02:43:37Z</updated>
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		<id>https://wikimd.org/index.php?title=Virulence&amp;diff=4969658&amp;oldid=prev</id>
		<title>Kondreddy Naveen at 23:14, 21 September 2023</title>
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		<updated>2023-09-21T23:14:30Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;== Virilization ==&lt;br /&gt;
&lt;br /&gt;
&amp;#039;&amp;#039;&amp;#039;Virilization&amp;#039;&amp;#039;&amp;#039; is a medical term describing the development of [[male]] physical and physiological characteristics in an individual, usually a [[woman]], who typically shouldn&amp;#039;t exhibit them. This condition is most commonly the result of an excess of male sex [[hormones]], particularly testosterone.&lt;br /&gt;
&lt;br /&gt;
[[File:Meissonier, his life and his art (1897) (14590776969).jpg|thumb|right|250px|Diagram illustrating the common signs of virilization.]]&lt;br /&gt;
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== Causes of Virilization ==&lt;br /&gt;
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The onset of virilization might be due to a variety of factors, though they predominantly stem from conditions or situations leading to an overproduction or exposure to androgens:&lt;br /&gt;
&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Ovarian Tumors&amp;#039;&amp;#039;&amp;#039;: Some tumors can produce androgens, leading to virilization.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Adrenal Tumors&amp;#039;&amp;#039;&amp;#039;: Tumors of the adrenal gland can also produce excessive androgens.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Polycystic Ovary Syndrome (PCOS)&amp;#039;&amp;#039;&amp;#039;: This common condition can lead to elevated androgen levels.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Congenital Adrenal Hyperplasia&amp;#039;&amp;#039;&amp;#039;: A genetic disorder resulting in altered hormone production.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Exogenous Androgens&amp;#039;&amp;#039;&amp;#039;: The intake of anabolic steroids or medications containing male hormones.&lt;br /&gt;
&lt;br /&gt;
== Signs and Symptoms ==&lt;br /&gt;
&lt;br /&gt;
While the specific manifestations can vary, common signs of virilization include:&lt;br /&gt;
&lt;br /&gt;
* Deepening of the voice.&lt;br /&gt;
* Increased body and facial hair ([[hirsutism]]).&lt;br /&gt;
* Enlarged [[clitoris]].&lt;br /&gt;
* Male-pattern baldness or hair thinning.&lt;br /&gt;
* Increased muscle mass.&lt;br /&gt;
* Changes in body shape towards a more male-like physique.&lt;br /&gt;
* Menstrual irregularities or cessation.&lt;br /&gt;
&lt;br /&gt;
== Diagnosis ==&lt;br /&gt;
&lt;br /&gt;
If virilization is suspected, a thorough evaluation is necessary:&lt;br /&gt;
&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Medical History&amp;#039;&amp;#039;&amp;#039;: To understand the onset and progression of symptoms.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Physical Examination&amp;#039;&amp;#039;&amp;#039;: To assess the extent of masculinization.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Laboratory Tests&amp;#039;&amp;#039;&amp;#039;: Blood tests to measure hormone levels.&lt;br /&gt;
* &amp;#039;&amp;#039;&amp;#039;Imaging Studies&amp;#039;&amp;#039;&amp;#039;: Ultrasound, CT, or MRI to identify tumors or cysts in the ovaries or adrenal glands.&lt;br /&gt;
&lt;br /&gt;
== Treatment ==&lt;br /&gt;
&lt;br /&gt;
The approach to treating virilization largely depends on its cause:&lt;br /&gt;
&lt;br /&gt;
* Surgical removal of tumors producing excessive androgens.&lt;br /&gt;
* Medications to suppress androgen production or block their effects.&lt;br /&gt;
* Hormone therapy, especially in congenital adrenal hyperplasia.&lt;br /&gt;
&lt;br /&gt;
Treatment can reverse some symptoms, but others, like voice deepening, might be permanent.&lt;br /&gt;
&lt;br /&gt;
== See Also ==&lt;br /&gt;
&lt;br /&gt;
* [[Testosterone]]&lt;br /&gt;
* [[Androgen]]&lt;br /&gt;
* [[Polycystic Ovary Syndrome]]&lt;br /&gt;
* [[Congenital Adrenal Hyperplasia]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&lt;br /&gt;
&amp;lt;references/&amp;gt;&lt;br /&gt;
&lt;br /&gt;
[[Category:Medical Conditions]]&lt;br /&gt;
[[Category:Endocrine Disorders]]&lt;br /&gt;
[[Category:Hormonal Imbalances]]&lt;br /&gt;
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		<author><name>Kondreddy Naveen</name></author>
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