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	~~'''Vacuum Splint'''~~		{{DISPLAYTITLE:ViroPharma}}

	~~A '''~~[[~~Vacuum Splint]]''' is a type of [[medical device]~~] ~~used in [[emergency medicine~~]] and [[sports medicine]] to immobilize a patient's limb in the event of a fracture or injury. It is a flexible, adjustable device that can be molded to the shape of the injured limb, providing support and reducing movement to prevent further injury.		[[File:ViroPharma_Corporate_Logo.png\|thumb\|right\|ViroPharma Corporate Logo]]

	~~== Function ==~~		'''ViroPharma''' was a biopharmaceutical company that focused on the development and commercialization of products for the treatment of diseases caused by viral infections. The company was known for its work in the field of [[infectious diseases]], particularly in developing therapies for [[hepatitis C]] and [[hereditary angioedema]].

	~~The vacuum splint works by removing air from the splint, which causes it to become rigid~~ and ~~conform to the shape of the patient's limb. This provides a secure and comfortable fit~~, ~~reducing pain and preventing further injury~~. The ~~vacuum splint is often used in conjunction~~ with a [[~~splint pump~~]] to ~~create the vacuum~~.		==History==
			ViroPharma was founded in 1994 and was headquartered in [[Exton, Pennsylvania]]. The company initially focused on developing antiviral drugs, with a particular emphasis on [[hepatitis C virus]] (HCV) and [[cytomegalovirus]] (CMV) infections. Over the years, ViroPharma expanded its research and development efforts to include other areas of unmet medical need.

	~~== Advantages ==~~		In 2004, ViroPharma acquired the rights to [[Vancocin]], an antibiotic used to treat [[Clostridium difficile]] infections, which became a significant part of its product portfolio. This acquisition marked a strategic shift for the company, allowing it to diversify its offerings beyond antiviral therapies.

	~~Compared to traditional rigid splints, vacuum splints have~~ several advantages. They are lightweight, easy to apply, and can be adjusted to fit any size or shape of limb. They also provide a more even distribution of pressure, which can help to reduce swelling and discomfort.		==Products==
			ViroPharma's product portfolio included several key therapies:

	~~== Disadvantages ==~~		* '''Vancocin''': An oral antibiotic used to treat [[Clostridium difficile]]-associated diarrhea. Vancocin was one of the company's most successful products, contributing significantly to its revenue.

	~~Despite their advantages, vacuum splints also have some disadvantages. They can be punctured or damaged, which would cause them to lose their rigidity~~. ~~They also require a pump to create~~ the ~~vacuum, which may not always be available~~ in ~~emergency situations~~.		* '''Cinryze''': A C1 esterase inhibitor used for the treatment of [[hereditary angioedema]] (HAE). Cinryze was approved by the [[Food and Drug Administration]] (FDA) in 2008 and became a cornerstone of ViroPharma's offerings.

	== ~~Usage~~ ==		==Acquisition==
			In 2014, ViroPharma was acquired by [[Shire plc]], a global biopharmaceutical company. The acquisition was valued at approximately $4.2 billion and was part of Shire's strategy to expand its rare disease portfolio. Following the acquisition, ViroPharma's products, including Cinryze, were integrated into Shire's operations.

	~~Vacuum splints are commonly used~~ in ~~[[emergency medical services]], [[sports medicine]]~~, and ~~[[military medicine]]~~. ~~They are particularly useful~~ in ~~situations where the patient needs~~ to ~~be transported, as they can be easily adjusted and removed if necessary~~.		==Research and Development==
			ViroPharma was actively involved in research and development, focusing on innovative therapies for viral infections and rare diseases. The company invested in clinical trials and collaborations with academic institutions to advance its pipeline of potential treatments.

	== ~~See Also~~ ==		==Legacy==
			ViroPharma's contributions to the field of biopharmaceuticals, particularly in the treatment of rare diseases and infectious diseases, have had a lasting impact. The company's focus on unmet medical needs and its successful development of therapies like Cinryze have been recognized as significant achievements in the industry.

	* [[~~Splint (medicine)~~]]		==Related pages==
	* [[~~Emergency medicine~~]]		* [[Biopharmaceutical]]
	* [[~~Sports medicine~~]]		* [[Hereditary angioedema]]
			* [[Clostridium difficile]]
			* [[Shire plc]]

	~~== References ==~~		[[Category:Biopharmaceutical companies]]
			[[Category:Defunct companies of the United States]]
	~~<references />~~		[[Category:Companies established in 1994]]
			[[Category:Companies disestablished in 2014]]
	[[Category:~~Medical devices~~]]
	[[Category:~~Emergency medical equipment~~]]
	[[Category:~~Sports medicine~~]]

	~~{{stub}}~~

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2024-02-25T16:51:06Z

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'''Vacuum Splint'''

A '''[[Vacuum Splint]]''' is a type of [[medical device]] used in [[emergency medicine]] and [[sports medicine]] to immobilize a patient's limb in the event of a fracture or injury. It is a flexible, adjustable device that can be molded to the shape of the injured limb, providing support and reducing movement to prevent further injury.

== Function ==

The vacuum splint works by removing air from the splint, which causes it to become rigid and conform to the shape of the patient's limb. This provides a secure and comfortable fit, reducing pain and preventing further injury. The vacuum splint is often used in conjunction with a [[splint pump]] to create the vacuum.

== Advantages ==

Compared to traditional rigid splints, vacuum splints have several advantages. They are lightweight, easy to apply, and can be adjusted to fit any size or shape of limb. They also provide a more even distribution of pressure, which can help to reduce swelling and discomfort.

== Disadvantages ==

Despite their advantages, vacuum splints also have some disadvantages. They can be punctured or damaged, which would cause them to lose their rigidity. They also require a pump to create the vacuum, which may not always be available in emergency situations.

== Usage ==

Vacuum splints are commonly used in [[emergency medical services]], [[sports medicine]], and [[military medicine]]. They are particularly useful in situations where the patient needs to be transported, as they can be easily adjusted and removed if necessary.

== See Also ==

* [[Splint (medicine)]]
* [[Emergency medicine]]
* [[Sports medicine]]

== References ==

<references />

[[Category:Medical devices]]
[[Category:Emergency medical equipment]]
[[Category:Sports medicine]]

{{stub}}

ViroPharma - Revision history

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