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2025-02-13T04:00:38Z

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← Older revision		Revision as of 04:00, 13 February 2025
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	~~'''Vilanterol''' is a~~ long-acting beta~~-adrenoceptor~~ agonist ~~(LABA)~~ used in the ~~management~~ of ~~chronic obstructive pulmonary disease (COPD) and asthma. It is usually administered in combination with other medications, such as [[fluticasone furoate]] and [[umeclidinium bromide]].~~		{{Short description\|A long-acting beta agonist used in the treatment of respiratory diseases}}

	== ~~Mechanism of Action~~ ==		==Vilanterol==
			[[File:Vilanterol.svg\|thumb\|right\|Chemical structure of Vilanterol]]
			'''Vilanterol''' is a [[long-acting beta agonist]] (LABA) used in the management of [[asthma]] and [[chronic obstructive pulmonary disease]] (COPD). It is often combined with other medications, such as [[inhaled corticosteroids]] or [[anticholinergics]], to enhance its therapeutic effects.

	Vilanterol works by stimulating ~~the~~ beta-2 adrenergic receptors in the ~~lungs~~, ~~which causes the muscles~~ in ~~the airways to relax~~. ~~This helps to open the airways and makes~~ it ~~easier~~ for ~~the patient to breathe~~.		==Pharmacology==
			Vilanterol works by stimulating [[beta-2 adrenergic receptors]] in the [[bronchioles]], leading to [[bronchodilation]] and improved airflow in patients with obstructive airway diseases. As a LABA, it provides prolonged bronchodilation, making it suitable for once-daily dosing.

	== ~~Uses~~ ==		===Mechanism of Action===
			Vilanterol binds to beta-2 adrenergic receptors on the smooth muscle cells of the airways. This binding activates [[adenylate cyclase]], increasing the levels of [[cyclic adenosine monophosphate]] (cAMP). Elevated cAMP levels lead to the relaxation of bronchial smooth muscle, resulting in bronchodilation.

	Vilanterol is used in the treatment of:		==Clinical Use==
			Vilanterol is primarily used in combination with other agents for the treatment of asthma and COPD. It is not recommended for use as a monotherapy due to the risk of asthma-related death associated with LABAs when used alone.

	* [[Chronic Obstructive Pulmonary Disease (COPD)]]		===Combination Products===
	* [[Asthma]]		Vilanterol is available in combination with:
			* [[Fluticasone furoate]], an inhaled corticosteroid, marketed under the brand name Breo Ellipta.
	It is ~~not used on its own, but~~ in combination with ~~other medications such as fluticasone furoate (a corticosteroid) and umeclidinium bromide (a long-acting muscarinic antagonist).~~		* [[Umeclidinium]], an anticholinergic, marketed under the brand name Anoro Ellipta.

	~~== Side Effects ==~~

	~~Like all medications, vilanterol can cause side effects. These may include~~:

	* [[~~Headache~~]]
	* [[~~Throat irritation~~]]
	* [[Nausea]]
	* [[Muscle cramps]]

	~~If you experience any severe or persistent side effects~~, ~~you should contact your healthcare provider immediately~~.

	== ~~Precautions~~ ==		==Side Effects==
			Common side effects of vilanterol include [[headache]], [[throat irritation]], and [[cough]]. Serious side effects may include [[paradoxical bronchospasm]], [[tachycardia]], and [[hypokalemia]].

	~~Before using vilanterol~~, ~~you should tell your healthcare provider if you have any other medical conditions~~, ~~especially:~~		==Contraindications==
			Vilanterol is contraindicated in patients with a history of hypersensitivity to the drug or any of its components. It should be used with caution in patients with cardiovascular disorders, [[thyrotoxicosis]], or [[diabetes mellitus]].

	* [[Heart disease]]		==Related pages==
	* [[High blood pressure]]
	* [[Diabetes]]
	* [[Thyroid disorder]]
	* [[Seizures]]
	* [[Liver disease]]

	~~You should also tell your healthcare provider about all other medications you are taking, as vilanterol can interact with other drugs.~~

	== ~~See Also~~ ==

	* [[Long-acting beta-adrenoceptor agonist]]
	* [[Chronic Obstructive Pulmonary Disease]]
	* [[Asthma]]		* [[Asthma]]
			* [[Chronic obstructive pulmonary disease]]
			* [[Beta-2 adrenergic receptor]]
			* [[Inhaled corticosteroid]]

	[[Category:~~Medicine~~]]		[[Category:Beta-2 adrenergic agonists]]
	[[Category:~~Pharmacology~~]]		[[Category:Respiratory drugs]]
	~~[[Category:Drugs]]~~

	~~{{stub}}~~

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2024-02-25T18:19:59Z

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'''Vilanterol''' is a long-acting beta-adrenoceptor agonist (LABA) used in the management of chronic obstructive pulmonary disease (COPD) and asthma. It is usually administered in combination with other medications, such as [[fluticasone furoate]] and [[umeclidinium bromide]].

== Mechanism of Action ==

Vilanterol works by stimulating the beta-2 adrenergic receptors in the lungs, which causes the muscles in the airways to relax. This helps to open the airways and makes it easier for the patient to breathe.

== Uses ==

Vilanterol is used in the treatment of:

* [[Chronic Obstructive Pulmonary Disease (COPD)]]
* [[Asthma]]

It is not used on its own, but in combination with other medications such as fluticasone furoate (a corticosteroid) and umeclidinium bromide (a long-acting muscarinic antagonist).

== Side Effects ==

Like all medications, vilanterol can cause side effects. These may include:

* [[Headache]]
* [[Throat irritation]]
* [[Nausea]]
* [[Muscle cramps]]

If you experience any severe or persistent side effects, you should contact your healthcare provider immediately.

== Precautions ==

Before using vilanterol, you should tell your healthcare provider if you have any other medical conditions, especially:

* [[Heart disease]]
* [[High blood pressure]]
* [[Diabetes]]
* [[Thyroid disorder]]
* [[Seizures]]
* [[Liver disease]]

You should also tell your healthcare provider about all other medications you are taking, as vilanterol can interact with other drugs.

== See Also ==

* [[Long-acting beta-adrenoceptor agonist]]
* [[Chronic Obstructive Pulmonary Disease]]
* [[Asthma]]

[[Category:Medicine]]
[[Category:Pharmacology]]
[[Category:Drugs]]

{{stub}}

Vilanterol - Revision history

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Prab: CSV import