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<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 21:04, 8 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=UGT1A9&diff=5379181&oldid=prev 2024-03-10T06:05:36Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;UGT1A9&#039;&#039;&#039; is an enzyme that in humans is encoded by the UGT1A9 gene. It is part of the [[UDP-glucuronosyltransferase]] (UGT) family, which plays a significant role in the [[metabolism]] of endogenous and exogenous compounds.<br /> <br /> == Function ==<br /> <br /> [[UGT1A9]] is involved in the process of [[glucuronidation]], a major part of phase II metabolism. Glucuronidation involves the addition of a glucuronic acid molecule to a substrate, thereby increasing its water solubility and facilitating its excretion from the body. This process is crucial in the metabolism of a wide range of substances, including drugs, environmental toxins, and endogenous compounds.<br /> <br /> == Clinical significance ==<br /> <br /> Variations in the UGT1A9 gene can affect the function of the enzyme, potentially leading to altered drug metabolism. This can have significant implications for drug efficacy and toxicity. For example, UGT1A9 is involved in the metabolism of [[nonsteroidal anti-inflammatory drugs]] (NSAIDs), and variations in this gene can affect an individual&#039;s response to these medications.<br /> <br /> == See also ==<br /> <br /> * [[UDP-glucuronosyltransferase]]<br /> * [[Glucuronidation]]<br /> * [[Drug metabolism]]<br /> <br /> == References ==<br /> <br /> &lt;references /&gt;<br /> <br /> == External links ==<br /> <br /> * [https://www.ncbi.nlm.nih.gov/gene/54600 UGT1A9] at the National Center for Biotechnology Information<br /> <br /> [[Category:Enzymes]]<br /> [[Category:Human proteins]]<br /> [[Category:Genes]]<br /> [[Category:Pharmacogenetics]]<br /> <br /> {{medicine-stub}}</div>

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