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	~~== Trunk Neural Crest ==~~

	~~[[File:~~Neural ~~crest cells.svg~~\|~~thumb~~\|~~right~~\|~~300px~~\|~~Illustration of neural~~ crest ~~cells. The trunk neural crest is a specific type of these cells.~~]]		{{Infobox anatomy
			\| Name = Trunk Neural Crest
			\| Latin = crista neuralis trunci
			\| Image = <!-- Image file name -->
			\| Caption = <!-- Image caption -->
			\| System = [[Nervous system]]
			\| Precursor = [[Neural crest]]
			\| Gives rise to = [[Peripheral nervous system]], [[Melanocytes]], [[Adrenal medulla]]
			}}

	The '''~~Trunk Neural Crest~~''' ~~refers to~~ a ~~group~~ of [[neural crest]] ~~cells that migrate from the neural tube~~ during ~~the~~ embryonic development ~~of vertebrates~~. These cells are ~~unique~~ in ~~their multipotency, capable of differentiating into a variety of cell types, including [[neurons]], [[glial cells]], [[melanocytes]], and [[adrenal medulla]] cells~~.		The '''trunk neural crest''' is a population of cells that originates from the [[neural crest]] during embryonic development. These cells are crucial for the formation of various structures in the body.

	== Development ==		== Development ==
			The trunk neural crest cells emerge from the dorsal part of the [[neural tube]] and migrate to different parts of the embryo. They differentiate into a variety of cell types, including:

	[[~~File:Neural crest migration paths.svg\|thumb\|left\|300px\|Diagram showing~~ the ~~migration paths~~ of ~~neural crest cells, including~~ the ~~trunk neural crest.~~]]		* [[Sensory neurons]] of the [[dorsal root ganglia]]
			* [[Sympathetic neurons]]
			* [[Schwann cells]]
			* [[Melanocytes]]
			* Cells of the [[adrenal medulla]]

	~~During [[embryogenesis]], the trunk~~ neural crest cells ~~emerge from the dorsal neural tube and migrate ventrally. They~~ follow specific pathways~~, guided~~ by ~~a combination of~~ [[~~chemotaxis~~]]~~, [[haptotaxis]],~~ and [[~~mechanotaxis~~]]~~. The cells differentiate into various cell types depending on their final location~~.		== Migration ==
			Trunk neural crest cells follow specific migratory pathways to reach their destinations. These pathways are influenced by various [[molecular signals]] and [[extracellular matrix]] components.

	== Function ==		== Function ==
			The trunk neural crest is essential for the development of the [[peripheral nervous system]]. It contributes to the formation of the [[autonomic nervous system]], which regulates involuntary bodily functions.
	The trunk neural crest ~~cells play a crucial role in~~ the ~~formation~~ of the [[peripheral nervous system]]. ~~They give rise to the [[dorsal root ganglia]], which contain the cell bodies of sensory neurons. They also contribute~~ to the formation of the [[~~sympathetic~~ nervous system]], ~~producing the [[sympathetic ganglia]] and the adrenal medulla~~.

	== Clinical Significance ==		== Clinical Significance ==
			Defects in trunk neural crest development can lead to various medical conditions, such as:

	~~Abnormalities in the development or migration of trunk neural crest cells can lead to a variety of~~ [[~~congenital disorders~~]]~~, including~~ [[Hirschsprung's disease]]~~, [[neuroblastoma]], and~~ [[Waardenburg syndrome]].		* [[Neuroblastoma]]
			* [[Hirschsprung's disease]]
	~~== Research ==~~		* [[Waardenburg syndrome]]

	Research into the trunk neural crest has provided valuable insights into the mechanisms of cell migration, differentiation, and the development of the nervous system. It also has potential implications for the treatment of diseases such as [[cancer]] and [[neurodegenerative diseases]].

	== See Also ==		== See Also ==
			* [[Cranial neural crest]]
	* [[~~Neural~~ crest]]		* [[Cardiac neural crest]]
	* [[~~Neural tube~~]]		* [[Neural crest cells]]
	* [[~~Embryogenesis]]~~
	* [[Congenital disorders]]

	== References ==		== References ==
			{{Reflist}}

	~~<references~~ />		== External Links ==
			* [https://www.wikimd.com/wiki/Neural_crest Neural Crest on WikiMD]

	~~[[Category:Developmental biology]]~~
	[[Category:Embryology]]		[[Category:Embryology]]
	[[Category:Neuroscience]]		[[Category:Neuroscience]]
	[[Category:~~Cell~~ biology]]		[[Category:Developmental biology]]

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== Trunk Neural Crest ==

[[File:Neural crest cells.svg|thumb|right|300px|Illustration of neural crest cells. The trunk neural crest is a specific type of these cells.]]

The '''Trunk Neural Crest''' refers to a group of [[neural crest]] cells that migrate from the neural tube during the embryonic development of vertebrates. These cells are unique in their multipotency, capable of differentiating into a variety of cell types, including [[neurons]], [[glial cells]], [[melanocytes]], and [[adrenal medulla]] cells.

== Development ==

[[File:Neural crest migration paths.svg|thumb|left|300px|Diagram showing the migration paths of neural crest cells, including the trunk neural crest.]]

During [[embryogenesis]], the trunk neural crest cells emerge from the dorsal neural tube and migrate ventrally. They follow specific pathways, guided by a combination of [[chemotaxis]], [[haptotaxis]], and [[mechanotaxis]]. The cells differentiate into various cell types depending on their final location.

== Function ==

The trunk neural crest cells play a crucial role in the formation of the [[peripheral nervous system]]. They give rise to the [[dorsal root ganglia]], which contain the cell bodies of sensory neurons. They also contribute to the formation of the [[sympathetic nervous system]], producing the [[sympathetic ganglia]] and the adrenal medulla.

== Clinical Significance ==

Abnormalities in the development or migration of trunk neural crest cells can lead to a variety of [[congenital disorders]], including [[Hirschsprung's disease]], [[neuroblastoma]], and [[Waardenburg syndrome]].

== Research ==

Research into the trunk neural crest has provided valuable insights into the mechanisms of cell migration, differentiation, and the development of the nervous system. It also has potential implications for the treatment of diseases such as [[cancer]] and [[neurodegenerative diseases]].

== See Also ==

* [[Neural crest]]
* [[Neural tube]]
* [[Embryogenesis]]
* [[Congenital disorders]]

== References ==

<references />

[[Category:Developmental biology]]
[[Category:Embryology]]
[[Category:Neuroscience]]
[[Category:Cell biology]]

Trunk neural crest - Revision history

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