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<p><b>New page</b></p><div>[[File:Tropacocaine.svg|thumb|{{PAGENAME}}]]<br>'''Tropacocaine''' is a [[tropane alkaloid]] that is found naturally in the [[coca plant]]. It is a [[local anesthetic]] that is structurally similar to [[cocaine]]. Tropacocaine was first isolated from the coca plant in 1891.<br />
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== History ==<br />
Tropacocaine was first isolated from the coca plant in 1891 by the German chemist [[Richard Willstätter]]. Willstätter was studying the chemical composition of the coca plant and discovered that tropacocaine was one of the plant's primary alkaloids.<br />
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== Chemistry ==<br />
Tropacocaine is a tropane alkaloid, which means it is a naturally occurring chemical compound that contains a [[tropane]] ring structure. This structure is composed of a seven-membered ring with a nitrogen atom and two additional carbon atoms. Tropacocaine is structurally similar to cocaine, but it has a different arrangement of atoms within the tropane ring.<br />
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== Pharmacology ==<br />
Tropacocaine acts as a local anesthetic by blocking [[sodium channels]] in nerve cells, which prevents the transmission of nerve impulses. This results in a loss of sensation in the area where the drug is applied. Tropacocaine is less potent than cocaine as a local anesthetic, but it has a shorter duration of action.<br />
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== Medical Use ==<br />
Tropacocaine is used in medical settings as a local anesthetic, particularly in ophthalmology. It is applied topically to numb the surface of the eye before procedures such as cataract surgery.<br />
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== Legal Status ==<br />
In many countries, including the United States, tropacocaine is a controlled substance due to its structural similarity to cocaine. It is classified as a Schedule II controlled substance under the [[Controlled Substances Act]] in the United States.<br />
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== See Also ==<br />
* [[Cocaine]]<br />
* [[Local anesthetic]]<br />
* [[Tropane alkaloids]]<br />
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[[Category:Pharmacology]]<br />
[[Category:Local anesthetics]]<br />
[[Category:Tropane alkaloids]]<br />
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