https://wikimd.org/index.php?action=history&feed=atom&title=Tn_antigen 2026-04-26T04:42:45Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Tn_antigen&diff=6522838&oldid=prev 2025-03-18T02:35:20Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 02:35, 18 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l19">Line 19:</td> <td colspan="2" class="diff-lineno">Line 19:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{cancer-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{cancer-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=Tn_antigen&diff=6274242&oldid=prev 2025-02-11T04:03:53Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:03, 11 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l18">Line 18:</td> <td colspan="2" class="diff-lineno">Line 18:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{cancer-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{cancer-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=Tn_antigen&diff=5455447&oldid=prev 2024-03-26T20:25:35Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Tn antigen&#039;&#039;&#039; is a [[carbohydrate]] [[antigen]] that is considered an important biomarker in the field of [[oncology]], particularly in the diagnosis and monitoring of certain types of [[cancer]]. The presence of Tn antigen is associated with [[tumor]] progression and metastasis, making it a significant target for [[cancer research]] and [[therapeutic]] strategies.<br /> <br /> ==Overview==<br /> Tn antigen is a simple [[O-linked glycan]] that consists of a single [[N-acetylgalactosamine]] (GalNAc) molecule attached to the hydroxyl group of serine or threonine residues in [[glycoproteins]]. This antigen is normally found in the human body in a highly modified form, as part of complex [[polysaccharides]]. However, in cancerous cells, due to aberrant [[glycosylation]] processes, the unmodified Tn antigen is expressed on the cell surface. This abnormal expression is implicated in the evasion of immune surveillance, tumor growth, and metastasis.<br /> <br /> ==Clinical Significance==<br /> The detection of Tn antigen in [[serum]] or on the surface of cells can serve as a diagnostic and prognostic marker for various types of cancers, including [[breast cancer]], [[prostate cancer]], and [[colorectal cancer]]. Its presence is often associated with a poor prognosis due to its role in facilitating tumor cell invasiveness and metastasis.<br /> <br /> ==Tn Antigen in Cancer Therapy==<br /> Research into targeting the Tn antigen for cancer therapy is ongoing. Strategies include the development of [[vaccines]] that elicit an immune response against tumor cells expressing the Tn antigen, and the creation of [[antibodies]] that specifically target this antigen. These approaches aim to improve the specificity of cancer treatments, reducing the impact on healthy cells and potentially leading to better outcomes for patients.<br /> <br /> ==Related Glycan Antigens==<br /> The Tn antigen is closely related to other glycan antigens, such as the [[T antigen]] (also known as the Thomsen-Friedenreich antigen) and the sialyl-Tn antigen. These antigens share similar pathways of aberrant glycosylation in cancer cells and are studied for their roles in tumor biology and their potential as biomarkers and therapeutic targets.<br /> <br /> [[Category:Oncology]]<br /> [[Category:Glycobiology]]<br /> [[Category:Cancer biomarkers]]<br /> <br /> {{cancer-stub}}</div>

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