https://wikimd.org/index.php?action=history&feed=atom&title=ThozalinoneThozalinone - Revision history2026-04-26T13:50:44ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Thozalinone&diff=6310362&oldid=prevPrab: CSV import2025-02-18T01:06:20Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''Thozalinone''' is a [[stimulant]] that was developed in the 1960s as a medication for [[depression]] and [[obesity]]. It is a [[cognitive enhancer]] and [[dopaminergic]] stimulant, which means it increases the activity of the [[neurotransmitter]] [[dopamine]] in the brain. Thozalinone was developed by the [[pharmaceutical company]] [[Upjohn]] (now part of [[Pfizer]]) but is no longer marketed.<br />
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==Pharmacology==<br />
Thozalinone works by inhibiting the reuptake of dopamine, which increases the amount of dopamine in the brain. This can lead to increased [[alertness]], [[attention]], and [[motivation]], as well as decreased [[fatigue]] and [[appetite]]. Thozalinone is structurally related to other stimulants like [[amphetamine]] and [[methylphenidate]], but it is not a [[controlled substance]] in most countries.<br />
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==Medical uses==<br />
Thozalinone was originally developed for the treatment of depression and obesity. However, it is no longer marketed for these uses. It has been studied for potential use in the treatment of [[attention deficit hyperactivity disorder]] (ADHD), but it is not currently approved for this use.<br />
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==Side effects==<br />
Like other stimulants, thozalinone can cause side effects such as [[insomnia]], [[anxiety]], [[agitation]], and [[increased heart rate]]. It can also cause [[psychosis]] in some individuals, especially at high doses or in those with a history of mental illness.<br />
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==See also==<br />
* [[List of stimulants]]<br />
* [[List of antidepressants]]<br />
* [[List of obesity medications]]<br />
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[[Category:Stimulants]]<br />
[[Category:Antidepressants]]<br />
[[Category:Obesity medications]]<br />
[[Category:Upjohn]]<br />
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