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			<gallery>
			File:Testosterone_decanoate.svg\|Chemical structure of Testosterone decanoate
			File:Testosterone_decanoate_molecule_ball.png\|Ball-and-stick model of Testosterone decanoate
			</gallery>

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'''Testosterone decanoate''' is an [[androgen]] and [[anabolic steroid]] (AAS) medication which is used mainly in the treatment of [[low testosterone]] levels in men.<ref>{{cite web|title=Testosterone Decanoate - an overview|url=https://www.sciencedirect.com/topics/neuroscience/testosterone-decanoate|access-date=2021-09-30}}</ref> It is also used in [[hormone therapy]] for transgender men.<ref>{{cite web|title=Testosterone therapy in transgender men|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686655/|access-date=2021-09-30}}</ref> It is given by [[injection into muscle]] usually once every one to four weeks.<ref>{{cite web|title=Testosterone Decanoate|url=https://www.drugs.com/international/testosterone-decanoate.html|access-date=2021-09-30}}</ref>

==Medical uses==
Testosterone decanoate is used primarily in [[androgen replacement therapy]]. It is specifically used to treat [[hypogonadism]] in men, which results in low testosterone levels.<ref>{{cite web|title=Testosterone therapy in men with hypogonadism|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188848/|access-date=2021-09-30}}</ref> It is also used in hormone therapy for transgender men.<ref>{{cite web|title=Testosterone therapy in transgender men|url=https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686655/|access-date=2021-09-30}}</ref>

==Side effects==
Side effects of testosterone decanoate include [[symptoms of masculinization]] like [[acne]], [[increased hair growth]], [[voice changes]], and increased sexual desire.<ref>{{cite web|title=Testosterone therapy: Potential benefits and risks as you age|url=https://www.mayoclinic.org/healthy-lifestyle/sexual-health/in-depth/testosterone-therapy/art-20045728|access-date=2021-09-30}}</ref> The drug is a [[controlled substance]], specifically a [[Schedule III controlled substance]], which means it has a potential for abuse and dependence.<ref>{{cite web|title=Controlled Substances - Alphabetical Order|url=https://www.deadiversion.usdoj.gov/schedules/orangebook/c_cs_alpha.pdf|access-date=2021-09-30}}</ref>

==Pharmacology==
As an AAS, testosterone decanoate is an [[agonist]] of the [[androgen receptor]] (AR), the biological target of androgens like testosterone and [[dihydrotestosterone]] (DHT).<ref>{{cite web|title=Androgen receptor|url=https://www.genecards.org/cgi-bin/carddisp.pl?gene=AR|access-date=2021-09-30}}</ref> It has strong [[anabolic effects]] and weak [[androgenic effects]], which give it a mild side effect profile and make it especially suitable for use in women.<ref>{{cite web|title=Anabolic steroids|url=https://www.drugabuse.gov/publications/drugfacts/anabolic-steroids|access-date=2021-09-30}}</ref>

==See also==
* [[List of androgens/anabolic steroids]]
* [[Testosterone (medication)]]

==References==
<references />

[[Category:Androgens]]
[[Category:Anabolic steroids]]
[[Category:Testosterone]]
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Testosterone decanoate - Revision history

Prab: CSV import

Prab: CSV import