Prab: CSV import

2025-03-18T01:24:45Z

CSV import

← Older revision		Revision as of 01:24, 18 March 2025
Line 36:		Line 36:
	{{pharmacology-stub}}		{{pharmacology-stub}}
	{{No image}}		{{No image}}
			__NOINDEX__

Prab: CSV import

2025-02-11T01:19:05Z

CSV import

← Older revision		Revision as of 01:19, 11 February 2025
Line 35:		Line 35:

	{{pharmacology-stub}}		{{pharmacology-stub}}
			{{No image}}

Prab: CSV import

2024-03-08T20:00:50Z

CSV import

New page

'''Target Controlled Infusion''' (TCI) is a method of drug delivery used in [[anesthesia]] and [[critical care]] where the rate of infusion is adjusted to maintain a desired drug concentration in the body. This method is commonly used for drugs with a narrow therapeutic index, such as [[propofol]] and [[remifentanil]], where small changes in drug concentration can lead to significant changes in effect.

== Mechanism ==

The TCI system uses a computer algorithm to control the infusion pump, adjusting the rate of drug delivery based on the patient's weight, age, and other factors. The algorithm is based on [[pharmacokinetic]] and [[pharmacodynamic]] models, which describe how the body absorbs, distributes, metabolizes, and excretes the drug.

== Advantages ==

TCI has several advantages over traditional methods of drug delivery. It allows for more precise control of drug concentration, reducing the risk of overdose or underdose. It also allows for rapid adjustment of drug concentration, which can be beneficial in situations where the patient's condition changes rapidly.

== Disadvantages ==

Despite its advantages, TCI also has some disadvantages. The accuracy of the system depends on the accuracy of the pharmacokinetic and pharmacodynamic models, which can vary between individuals. In addition, the system requires a sophisticated infusion pump and computer algorithm, which can be expensive and require specialized training to use.

== Clinical Applications ==

TCI is commonly used in anesthesia and critical care for the delivery of drugs such as propofol and remifentanil. It is also used in [[pain management]], where it can provide a constant level of analgesia while minimizing side effects.

== See Also ==

* [[Pharmacokinetics]]
* [[Pharmacodynamics]]
* [[Anesthesia]]
* [[Critical care]]
* [[Pain management]]

== References ==

<references />

[[Category:Anesthesia]]
[[Category:Critical care]]
[[Category:Pharmacology]]
[[Category:Pain management]]

{{pharmacology-stub}}

Target controlled infusion - Revision history

Prab: CSV import

Prab: CSV import

Prab: CSV import