https://wikimd.com/index.php?action=history&feed=atom&title=TTP TTP - Revision history 2026-04-08T17:38:32Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=TTP&diff=6526531&oldid=prev Prab at 13:19, 18 March 2025 2025-03-18T13:19:23Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:19, 18 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; 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border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=TTP&diff=5296369&oldid=prev Prab: CSV import 2024-02-25T18:48:38Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Thrombotic thrombocytopenic purpura&#039;&#039;&#039; (&#039;&#039;&#039;TTP&#039;&#039;&#039;) is a rare blood disorder characterized by clotting in small blood vessels of the body (thromboses), resulting in a low platelet count.<br /> <br /> == Signs and symptoms ==<br /> The classic pentad of symptoms includes [[thrombocytopenia]], [[microangiopathic hemolytic anemia]], [[neurological abnormalities]], [[fever]], and [[renal disease]]. However, the full pentad is not always observed.<br /> <br /> == Causes ==<br /> TTP can be inherited or acquired. Inherited TTP, also known as Upshaw-Schulman syndrome, is caused by mutations in the [[ADAMTS13]] gene. Acquired TTP is often associated with [[autoimmune diseases]], [[pregnancy]], [[cancer]], [[HIV infection]], and certain medications.<br /> <br /> == Diagnosis ==<br /> Diagnosis of TTP is based on clinical findings and laboratory tests. The [[PLASMIC score]] can be used to predict the likelihood of TTP in patients with thrombocytopenia and microangiopathic hemolytic anemia.<br /> <br /> == Treatment ==<br /> Treatment typically involves [[plasma exchange]] and [[immunosuppressive drugs]]. In severe cases, [[rituximab]] may be used.<br /> <br /> == Prognosis ==<br /> With treatment, the majority of people with TTP can lead normal lives. However, relapses can occur.<br /> <br /> == See also ==<br /> * [[Hemolytic-uremic syndrome]]<br /> * [[Disseminated intravascular coagulation]]<br /> * [[Paroxysmal nocturnal hemoglobinuria]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Blood disorders]]<br /> [[Category:Rare diseases]]<br /> [[Category:Conditions diagnosed by hematologic tests]]<br /> {{stub}}</div> Prab