https://wikimd.org/index.php?action=history&feed=atom&title=Stamulumab Stamulumab - Revision history 2026-05-13T16:55:35Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Stamulumab&diff=6526343&oldid=prev Prab at 13:19, 18 March 2025 2025-03-18T13:19:02Z <p></p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 13:19, 18 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l24">Line 24:</td> <td colspan="2" class="diff-lineno">Line 24:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; 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font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #ffe49c; vertical-align: top; white-space: pre-wrap;"><div><del style="font-weight: bold; text-decoration: none;">__NOINDEX__</del></div></td><td colspan="2" class="diff-side-added"></td></tr> </table> Prab https://wikimd.org/index.php?title=Stamulumab&diff=6520768&oldid=prev Prab: CSV import 2025-03-18T01:24:56Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:24, 18 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l24">Line 24:</td> <td colspan="2" class="diff-lineno">Line 24:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; 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font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=Stamulumab&diff=6263350&oldid=prev Prab: CSV import 2025-02-10T23:17:00Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 23:17, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l23">Line 23:</td> <td colspan="2" class="diff-lineno">Line 23:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Muscular dystrophy]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Muscular dystrophy]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=Stamulumab&diff=5344852&oldid=prev Prab: CSV import 2024-03-02T16:34:35Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Stamulumab&#039;&#039;&#039; (also known as &#039;&#039;&#039;MYO-029&#039;&#039;&#039;) is an experimental [[myostatin]] inhibiting drug developed for the treatment of [[muscular dystrophy]] (MD). Stamulumab was developed by [[Wyeth Pharmaceuticals]], which was later acquired by [[Pfizer]].<br /> <br /> == History ==<br /> Stamulumab was first developed by Wyeth Pharmaceuticals in the early 2000s. The drug was part of a new class of treatments for MD that aimed to inhibit the production of myostatin, a protein that inhibits muscle growth. The idea was that by blocking myostatin, Stamulumab could help increase muscle mass and strength in people with MD.<br /> <br /> == Mechanism of Action ==<br /> Stamulumab is a [[monoclonal antibody]] that binds to myostatin and prevents it from binding to its receptor. This inhibits the signal that myostatin sends to muscle cells to stop growing, allowing the muscle cells to grow and multiply more than they would normally.<br /> <br /> == Clinical Trials ==<br /> Stamulumab has undergone several [[clinical trials]] to test its safety and efficacy. In a Phase I trial, the drug was found to be safe and well-tolerated. However, in a Phase II trial, the drug did not meet its primary endpoint of improving muscle strength. Despite this, some participants did see improvements in muscle mass and function, suggesting that the drug may still have potential for treating MD.<br /> <br /> == Current Status ==<br /> As of 2021, Stamulumab is not currently approved for use by any health regulatory authority. Pfizer, which acquired Wyeth in 2009, has not announced any plans to continue development of the drug.<br /> <br /> == See Also ==<br /> * [[Muscular dystrophy]]<br /> * [[Myostatin]]<br /> * [[Monoclonal antibody]]<br /> * [[Clinical trial]]<br /> <br /> [[Category:Experimental drugs]]<br /> [[Category:Monoclonal antibodies]]<br /> [[Category:Muscular dystrophy]]<br /> {{medicine-stub}}</div> Prab