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2025-02-18T05:00:02Z

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← Older revision		Revision as of 05:00, 18 February 2025
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			<gallery>
			File:Gray19_with_color.png\|Somite
			File:Gray20.png\|Somite
			File:Gray18.png\|Somite
			File:Gray64.png\|Somite
			File:Gray65.png\|Somite
			File:End_of_week_4_Embryo_with_somites.jpg\|End of week 4 embryo with somites
			</gallery>

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2024-02-25T17:08:45Z

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'''Somite''' is a division of the body of an animal or embryo. In humans, somites are spheres of mesoderm that form along the neural tube during embryonic development. They give rise to important structures such as the vertebral column, skeletal muscle, and dermis.

== Development ==
Somites are formed from the paraxial mesoderm. This process, known as [[somitogenesis]], begins in the third week of human embryonic development. The paraxial mesoderm is divided into segments, and each segment will eventually form a somite. The process of somitogenesis is controlled by a complex network of [[gene]]s and [[protein]]s.

== Structure ==
Each somite is composed of a dorsal part called the [[dermomyotome]], which gives rise to the dermis and skeletal muscle, and a ventral part called the [[sclerotome]], which forms the vertebral column. The dermomyotome is further divided into the myotome, which forms skeletal muscle, and the dermatome, which forms the dermis.

== Function ==
Somites play a crucial role in the development of the vertebrate body plan. They give rise to the segmented pattern of the vertebral column and play a role in the development of the peripheral nervous system. In addition, somites are involved in the formation of the axial skeleton, voluntary muscles, and dermis of the skin.

== Clinical significance ==
Abnormalities in somite development can lead to a variety of congenital disorders. These include [[vertebral segmentation disorders]] such as [[scoliosis]], [[kyphosis]], and [[spondylosis]]. In addition, somite abnormalities can result in [[muscular dystrophy]] and other muscle disorders.

== See also ==
* [[Embryogenesis]]
* [[Mesoderm]]
* [[Neural tube]]

== References ==
<references />

[[Category:Embryology]]
[[Category:Developmental biology]]
[[Category:Anatomy]]
{{stub}}

Somite - Revision history

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Prab: CSV import