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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Sigma-2_receptor</id>
	<title>Sigma-2 receptor - Revision history</title>
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	<updated>2026-04-26T20:13:22Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=Sigma-2_receptor&amp;diff=6342311&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Sigma-2_receptor&amp;diff=6342311&amp;oldid=prev"/>
		<updated>2025-02-23T21:32:06Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 21:32, 23 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l35&quot;&gt;Line 35:&lt;/td&gt;
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&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;br&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{stub}}&lt;/div&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot;&gt;&lt;/td&gt;&lt;td style=&quot;background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;{{stub}}&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;== Sigma-2 receptor ==&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;gallery&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;File:PET_scans_of_brain_tumor_using_Sigma-2_Ligands.png|PET scans of brain tumor using Sigma-2 Ligands&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-side-deleted&quot;&gt;&lt;/td&gt;&lt;td class=&quot;diff-marker&quot; data-marker=&quot;+&quot;&gt;&lt;/td&gt;&lt;td style=&quot;color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;&quot;&gt;&lt;div&gt;&lt;ins style=&quot;font-weight: bold; text-decoration: none;&quot;&gt;&amp;lt;/gallery&amp;gt;&lt;/ins&gt;&lt;/div&gt;&lt;/td&gt;&lt;/tr&gt;
&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Sigma-2_receptor&amp;diff=5295044&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Sigma-2_receptor&amp;diff=5295044&amp;oldid=prev"/>
		<updated>2024-02-25T17:50:51Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Sigma-2 receptor&amp;#039;&amp;#039;&amp;#039; is a protein that is part of the [[sigma receptor]] family of proteins. It is found in many different tissues in the body, including the brain, liver, and kidneys. The function of the sigma-2 receptor is not fully understood, but it is thought to play a role in [[cell proliferation]], [[cell death]], and [[neuroplasticity]]. &lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
&lt;br /&gt;
The sigma-2 receptor is thought to be involved in a number of different physiological processes. It has been shown to regulate [[cell proliferation]] and [[cell death]], and it may also play a role in [[neuroplasticity]], the ability of the brain to change and adapt in response to new experiences.&lt;br /&gt;
&lt;br /&gt;
In addition to these functions, the sigma-2 receptor is also thought to be involved in the regulation of [[lipid metabolism]], and it may play a role in the development of [[obesity]] and [[type 2 diabetes]].&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
&lt;br /&gt;
Because of its role in cell proliferation and death, the sigma-2 receptor is being investigated as a potential target for [[cancer therapy]]. Several drugs that target the sigma-2 receptor have been developed and are currently being tested in clinical trials.&lt;br /&gt;
&lt;br /&gt;
In addition, because of its role in neuroplasticity, the sigma-2 receptor is also being investigated as a potential target for the treatment of [[neurodegenerative diseases]], such as [[Alzheimer&amp;#039;s disease]] and [[Parkinson&amp;#039;s disease]].&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
&lt;br /&gt;
* [[Sigma receptor]]&lt;br /&gt;
* [[Cell proliferation]]&lt;br /&gt;
* [[Cell death]]&lt;br /&gt;
* [[Neuroplasticity]]&lt;br /&gt;
* [[Lipid metabolism]]&lt;br /&gt;
* [[Obesity]]&lt;br /&gt;
* [[Type 2 diabetes]]&lt;br /&gt;
* [[Cancer therapy]]&lt;br /&gt;
* [[Neurodegenerative diseases]]&lt;br /&gt;
* [[Alzheimer&amp;#039;s disease]]&lt;br /&gt;
* [[Parkinson&amp;#039;s disease]]&lt;br /&gt;
&lt;br /&gt;
[[Category:Proteins]]&lt;br /&gt;
[[Category:Cell biology]]&lt;br /&gt;
[[Category:Neuroscience]]&lt;br /&gt;
[[Category:Endocrinology]]&lt;br /&gt;
[[Category:Oncology]]&lt;br /&gt;
[[Category:Pharmacology]]&lt;br /&gt;
&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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