https://wikimd.org/index.php?action=history&feed=atom&title=ST-1936ST-1936 - Revision history2026-04-26T06:11:18ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=ST-1936&diff=6335577&oldid=prevPrab: CSV import2025-02-20T01:39:18Z<p>CSV import</p>
<table style="background-color: #fff; color: #202122;" data-mw="interface">
<col class="diff-marker" />
<col class="diff-content" />
<col class="diff-marker" />
<col class="diff-content" />
<tr class="diff-title" lang="en">
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td>
<td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 01:39, 20 February 2025</td>
</tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l31">Line 31:</td>
<td colspan="2" class="diff-lineno">Line 31:</td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr>
<tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{pharmacology-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{pharmacology-stub}}</div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"><gallery></ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:ST-1936 structure.svg|ST-1936</ins></div></td></tr>
<tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;"></gallery></ins></div></td></tr>
</table>Prabhttps://wikimd.org/index.php?title=ST-1936&diff=5375506&oldid=prevPrab: CSV import2024-03-08T19:15:37Z<p>CSV import</p>
<p><b>New page</b></p><div>'''ST-1936''' is a [[serotonin receptor]] agonist that is selective for the [[5-HT6 receptor]]. It was first synthesized and studied by a team of researchers in Italy. ST-1936 shows promise in the treatment of [[obesity]] and [[cognitive disorders]], including [[Alzheimer's disease]].<br />
<br />
==Chemistry==<br />
ST-1936 is a synthetic compound that belongs to the [[oxazolo[4,5-b]pyridine]] class. It is a highly selective agonist for the 5-HT6 receptor, with a binding affinity (Ki) of 13 nM. It has a molecular weight of 354.4 g/mol and a chemical formula of C20H19N3O2.<br />
<br />
==Pharmacology==<br />
ST-1936 acts as an agonist at the 5-HT6 receptor, a subtype of serotonin receptor that is primarily found in the [[central nervous system]]. By activating these receptors, ST-1936 can influence a variety of neurological processes.<br />
<br />
===Effects on Obesity===<br />
Preclinical studies have shown that ST-1936 can reduce food intake and body weight in rats. This suggests that it may have potential as a treatment for obesity.<br />
<br />
===Effects on Cognitive Function===<br />
ST-1936 has also been found to enhance cognitive function in animal models. It improves performance on memory tasks and increases [[neurogenesis]] in the [[hippocampus]], a region of the brain that is critical for learning and memory. This suggests that ST-1936 could be useful in the treatment of cognitive disorders such as Alzheimer's disease.<br />
<br />
==Potential Therapeutic Uses==<br />
Given its effects on food intake and cognitive function, ST-1936 could have potential therapeutic uses in the treatment of obesity and cognitive disorders. However, more research is needed to fully understand its mechanisms of action and to assess its safety and efficacy in humans.<br />
<br />
==See Also==<br />
* [[5-HT6 receptor]]<br />
* [[Serotonin receptor]]<br />
* [[Obesity]]<br />
* [[Cognitive disorders]]<br />
* [[Alzheimer's disease]]<br />
<br />
==References==<br />
<references/><br />
<br />
[[Category:Serotonin receptor agonists]]<br />
[[Category:Experimental drugs]]<br />
[[Category:Pharmacology]]<br />
<br />
{{pharmacology-stub}}</div>Prab