https://wikimd.org/index.php?action=history&feed=atom&title=SLC22A18SLC22A18 - Revision history2026-04-26T16:53:49ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=SLC22A18&diff=5379044&oldid=prevPrab: CSV import2024-03-10T05:56:11Z<p>CSV import</p>
<p><b>New page</b></p><div>'''SLC22A18''' is a gene that in humans is encoded by the SLC22A18 protein. It is also known as the '''solute carrier family 22 member 18''' gene. This gene is located on chromosome 11p15.5, a region which is associated with [[Beckwith-Wiedemann syndrome]], [[Wilms tumor]], [[rhabdomyosarcoma]], and [[lung cancer]].<br />
<br />
== Function ==<br />
The SLC22A18 gene is part of the [[solute carrier]] family, which is a large group of membrane transport proteins that facilitate the movement of a wide variety of solutes across biological membranes. The SLC22A18 protein is thought to play a role in the transport of small molecules.<br />
<br />
== Clinical significance ==<br />
Mutations in the SLC22A18 gene have been associated with several types of cancer. The gene is located in a region of chromosome 11 that is often deleted in [[neuroblastoma]], [[lung cancer]], and [[breast cancer]]. This has led to the suggestion that SLC22A18 may function as a [[tumor suppressor gene]].<br />
<br />
== Research ==<br />
Research into the SLC22A18 gene and its associated protein is ongoing. Current areas of investigation include the role of the gene in cancer development and progression, and its potential as a target for new cancer therapies.<br />
<br />
== See also ==<br />
* [[Solute carrier family]]<br />
* [[Tumor suppressor gene]]<br />
* [[Chromosome 11 (human)]]<br />
<br />
== References ==<br />
<references /><br />
<br />
[[Category:Genes]]<br />
[[Category:Human proteins]]<br />
[[Category:Membrane transport proteins]]<br />
[[Category:Cancer research]]<br />
{{medicine-stub}}</div>Prab