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SGLT2 inhibitor - Revision history
2026-04-27T05:26:39Z
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2024-02-25T15:25:28Z
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<p><b>New page</b></p><div>'''SGLT2 inhibitors''' or '''Sodium-glucose co-transporter-2 inhibitors''' are a class of [[medication]]s used primarily in the treatment of [[type 2 diabetes]]. They work by preventing the kidneys from reabsorbing glucose back into the blood, thereby promoting the excretion of glucose in urine.<br />
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== Mechanism of Action ==<br />
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SGLT2 inhibitors work by blocking the sodium-glucose co-transporter-2 (SGLT2), which is responsible for the majority of glucose reabsorption by the kidneys. By inhibiting this transporter, these medications increase the amount of glucose excreted in the urine, thereby lowering blood glucose levels.<br />
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== Uses ==<br />
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SGLT2 inhibitors are primarily used in the treatment of [[type 2 diabetes]]. They may also be used in the management of [[heart failure]] and [[chronic kidney disease]].<br />
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== Side Effects ==<br />
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Common side effects of SGLT2 inhibitors include [[urinary tract infections]], [[yeast infections]], and increased urination. Rare but serious side effects may include [[ketoacidosis]] and [[kidney injury]].<br />
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== Examples ==<br />
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Examples of SGLT2 inhibitors include [[canagliflozin]], [[dapagliflozin]], and [[empagliflozin]].<br />
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== See Also ==<br />
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* [[Type 2 diabetes]]<br />
* [[Heart failure]]<br />
* [[Chronic kidney disease]]<br />
* [[Medication]]<br />
* [[Canagliflozin]]<br />
* [[Dapagliflozin]]<br />
* [[Empagliflozin]]<br />
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[[Category:Medication]]<br />
[[Category:Diabetes]]<br />
[[Category:Heart failure]]<br />
[[Category:Chronic kidney disease]]<br />
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