https://wikimd.org/index.php?action=history&feed=atom&title=SCH-23390SCH-23390 - Revision history2026-05-01T01:14:12ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=SCH-23390&diff=6347291&oldid=prevPrab: CSV import2025-02-25T20:56:12Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''SCH-23390''' is a drug that acts as a potent and selective antagonist for the [[Dopamine receptor D1|D1-like dopamine receptor]]. It was the first selective antagonist for the D1 receptor to be discovered. SCH-23390 is often used in scientific research to study the effects of dopamine on the brain.<br />
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== Pharmacology ==<br />
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SCH-23390 acts as a potent and selective antagonist for the [[Dopamine receptor D1|D1-like dopamine receptor]]. It has a high affinity for the D1 receptor and a much lower affinity for the [[Dopamine receptor D2|D2 receptor]]. SCH-23390 is also a weak antagonist for the [[Serotonin receptor|5-HT2C receptor]] and the [[Adrenergic receptor|α1B-adrenergic receptor]].<br />
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== Uses ==<br />
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SCH-23390 is primarily used in scientific research to study the effects of dopamine on the brain. It is often used in animal studies to block the effects of drugs that increase dopamine activity, such as [[Cocaine|cocaine]] and [[Amphetamine|amphetamine]]. It has also been used in studies investigating the role of dopamine in [[Reward system|reward]], [[Motor coordination|motor coordination]], and [[Memory|memory]].<br />
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== Side Effects ==<br />
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As a research chemical, SCH-23390 is not intended for human consumption, so information on its side effects is limited. However, in animal studies, it has been shown to cause [[Hyperactivity|hyperactivity]], [[Agitation|agitation]], and [[Tremor|tremors]] when administered at high doses.<br />
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== See Also ==<br />
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* [[Dopamine receptor D1]]<br />
* [[Dopamine receptor D2]]<br />
* [[Serotonin receptor]]<br />
* [[Adrenergic receptor]]<br />
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[[Category:Drugs]]<br />
[[Category:Dopamine antagonists]]<br />
[[Category:Research chemicals]]<br />
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