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	<title>Ripasudil - Revision history</title>
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	<updated>2026-04-26T01:37:08Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=Ripasudil&amp;diff=6334931&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Ripasudil&amp;diff=6334931&amp;oldid=prev"/>
		<updated>2025-02-20T01:32:17Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 01:32, 20 February 2025&lt;/td&gt;
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		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Ripasudil&amp;diff=5297595&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Ripasudil&amp;diff=5297595&amp;oldid=prev"/>
		<updated>2024-02-25T21:00:08Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Ripasudil&amp;#039;&amp;#039;&amp;#039; (also known as &amp;#039;&amp;#039;&amp;#039;K-115&amp;#039;&amp;#039;&amp;#039;) is a [[drug]] used for the treatment of [[glaucoma]] and [[ocular hypertension]]. It is a [[ROCK inhibitor]], specifically inhibiting Rho-associated protein kinase (ROCK), which is involved in the regulation of the tone of smooth muscle and intraocular pressure.&lt;br /&gt;
&lt;br /&gt;
== Mechanism of Action ==&lt;br /&gt;
&lt;br /&gt;
Ripasudil works by inhibiting the Rho-associated protein kinase (ROCK), which is involved in the regulation of the tone of smooth muscle and intraocular pressure. This inhibition results in the relaxation of the [[Trabecular meshwork]], allowing for increased outflow of [[aqueous humor]] and a subsequent decrease in intraocular pressure.&lt;br /&gt;
&lt;br /&gt;
== Uses ==&lt;br /&gt;
&lt;br /&gt;
Ripasudil is primarily used for the treatment of glaucoma and ocular hypertension. It is often used when other treatments have failed or are not suitable. It can be used alone or in combination with other glaucoma medications.&lt;br /&gt;
&lt;br /&gt;
== Side Effects ==&lt;br /&gt;
&lt;br /&gt;
Common side effects of Ripasudil include [[conjunctival hyperemia]], [[corneal verticillata]], and [[instillation site]] pain or discomfort. Less common side effects can include [[blepharitis]], [[conjunctival hemorrhage]], and [[eye pruritus]].&lt;br /&gt;
&lt;br /&gt;
== History ==&lt;br /&gt;
&lt;br /&gt;
Ripasudil was approved for medical use in Japan in September 2014. It is marketed under the brand name Glanatec.&lt;br /&gt;
&lt;br /&gt;
== See Also ==&lt;br /&gt;
&lt;br /&gt;
* [[Rho kinase]]&lt;br /&gt;
* [[Glaucoma]]&lt;br /&gt;
* [[Ocular hypertension]]&lt;br /&gt;
&lt;br /&gt;
[[Category:Drugs]]&lt;br /&gt;
[[Category:Glaucoma]]&lt;br /&gt;
[[Category:Ocular hypertension]]&lt;br /&gt;
[[Category:ROCK inhibitors]]&lt;br /&gt;
&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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