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			<gallery>
			File:Lac_Operon.svg\|Lac Operon
			File:Structure_of_L-arabinose_operon_of_E._coli.tif\|Structure of L-arabinose operon of E. coli
			File:L-arabinose_structure.png\|L-arabinose structure
			</gallery>

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2024-02-23T22:14:31Z

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'''Repressor'''

A '''[[Repressor]]''' is a [[DNA-binding protein]] that regulates the expression of one or more [[genes]] by binding to the [[operator (genetics)|operator]] or associated [[silencers]]. A DNA-binding repressor blocks the attachment of [[RNA polymerase]] to the [[promoter (genetics)|promoter]], thus preventing [[transcription (genetics)|transcription]] of the genes into [[messenger RNA]]. Some repressors are [[allosteric proteins]] that change their binding affinity to the operator in the presence of a small molecule [[ligand]].

== Function ==

Repressors are common types of [[transcription factor]]s in prokaryotes. They function by binding to the operator, a specific DNA sequence upstream of the promoter. This binding blocks RNA polymerase from initiating transcription. Repressors can be classified into two types: those that bind to the operator in the absence of a corepressor and those that bind in the presence of an inducer.

== Types of Repressors ==

=== Aporepressor ===

An '''[[Aporepressor]]''' is a repressor that binds to the operator in the absence of a corepressor. This type of repressor is inactive when binding to the operator and requires a corepressor to function.

=== Holorepressor ===

A '''[[Holorepressor]]''' is a repressor that binds to the operator in the presence of an inducer. This type of repressor is active when binding to the operator and does not require a corepressor to function.

== See Also ==

* [[Operator (genetics)]]
* [[Promoter (genetics)]]
* [[Transcription factor]]
* [[Gene expression]]

== References ==

<references />

[[Category:Genetics]]
[[Category:Protein]]
[[Category:DNA-binding proteins]]
[[Category:Transcription factors]]

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Repressor - Revision history

Prab: CSV import

Prab: CSV import