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			== RecBCD ==
			<gallery>
			File:RecBCD_1W36.png\|RecBCD 1W36
			File:Chi_Recombination_Model_for_Wikipedia.tif\|Chi Recombination Model for Wikipedia
			File:HR_RecBCD_RecA.svg\|HR RecBCD RecA
			</gallery>

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'''RecBCD''' is an [[enzyme]] complex found in [[Escherichia coli]] (E. coli) and many other [[bacteria]]. The main function of RecBCD is to repair [[DNA]] that has been damaged. It does this by [[homologous recombination]], a process that involves exchanging genetic information between two similar or identical strands of DNA.

== Structure ==
RecBCD is made up of three subunits: RecB, RecC, and RecD. Each subunit plays a unique role in the function of the enzyme complex. RecB is a [[helicase]] and [[nuclease]], RecC recognizes specific DNA sequences, and RecD is another helicase.

== Function ==
The primary role of RecBCD is to repair double-strand breaks in DNA. These breaks can occur as a result of damage from [[ultraviolet light]], [[radiation]], or chemicals. RecBCD repairs these breaks through a process called homologous recombination.

In addition to its role in DNA repair, RecBCD also plays a role in the process of [[bacterial conjugation]], which is a type of [[genetic recombination]] that involves the transfer of DNA from one bacterium to another.

== Mechanism ==
The mechanism of RecBCD involves several steps. First, the enzyme binds to a double-strand break in the DNA. Then, it unwinds and separates the two strands of DNA. As it moves along the DNA, it degrades one strand while leaving the other intact. When it reaches a specific sequence of DNA known as a Chi site, it stops degrading the DNA and begins the process of recombination.

== Clinical significance ==
Because of its role in DNA repair and recombination, RecBCD is of interest in the study of [[genetic diseases]] and [[cancer]]. Mutations in the genes that encode the RecBCD complex can lead to an increased risk of these conditions.

== See also ==
* [[DNA repair]]
* [[Homologous recombination]]
* [[Bacterial conjugation]]

== References ==
<references />

[[Category:DNA repair]]
[[Category:Enzymes]]
[[Category:Bacterial conjugation]]
[[Category:Genetic recombination]]

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RecBCD - Revision history

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