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			{{SI}}
			{{Infobox medical condition
			\| name = Rachischisis
			\| image = [[File:Craniorachischisis_(mouse).png\|250px]]
			\| caption = Rachischisis in a mouse model
			\| field = [[Neurology]], [[Pediatrics]]
			\| synonyms = Spinal dysraphism
			\| symptoms = [[Paralysis]], [[Hydrocephalus]], [[Clubfoot]], [[Anencephaly]]
			\| complications = [[Infection]], [[Neurological deficits]]
			\| onset = [[Congenital]]
			\| duration = Lifelong
			\| causes = [[Neural tube defect]]
			\| risks = [[Folic acid deficiency]], [[Genetic factors]]
			\| diagnosis = [[Prenatal ultrasound]], [[MRI]]
			\| differential = [[Spina bifida]], [[Anencephaly]]
			\| prevention = [[Folic acid supplementation]]
			\| treatment = [[Surgical repair]], [[Supportive care]]
			\| prognosis = Variable, often poor
			\| frequency = Rare
			}}
	'''Rachischisis''' is a severe form of [[Spina Bifida\|spina bifida]] in which the [[vertebral arch]]es and [[neural tube]] fail to close, resulting in an open spinal column. This condition is typically evident at birth and can lead to significant neurological complications.		'''Rachischisis''' is a severe form of [[Spina Bifida\|spina bifida]] in which the [[vertebral arch]]es and [[neural tube]] fail to close, resulting in an open spinal column. This condition is typically evident at birth and can lead to significant neurological complications.

	==Etiology==		==Etiology==
	The exact cause of rachischisis is unknown, but it is believed to be a combination of genetic and environmental factors. Some studies suggest a link between the mother's diet during pregnancy, particularly a deficiency in [[Folic Acid\|folic acid]], and the development of neural tube defects like rachischisis.		The exact cause of rachischisis is unknown, but it is believed to be a combination of genetic and environmental factors. Some studies suggest a link between the mother's diet during pregnancy, particularly a deficiency in [[Folic Acid\|folic acid]], and the development of neural tube defects like rachischisis.

	==Symptoms==		==Symptoms==
	The most obvious symptom of rachischisis is a visible opening in the spine at birth. Other symptoms can include neurological problems, such as [[Paralysis\|paralysis]] and [[Hydrocephalus\|hydrocephalus]], as well as issues with bladder and bowel control.		The most obvious symptom of rachischisis is a visible opening in the spine at birth. Other symptoms can include neurological problems, such as [[Paralysis\|paralysis]] and [[Hydrocephalus\|hydrocephalus]], as well as issues with bladder and bowel control.

	==Diagnosis==		==Diagnosis==
	Rachischisis can often be diagnosed before birth through [[Ultrasound\|ultrasound]] imaging. After birth, a physical examination of the newborn can confirm the diagnosis.		Rachischisis can often be diagnosed before birth through [[Ultrasound\|ultrasound]] imaging. After birth, a physical examination of the newborn can confirm the diagnosis.

	==Treatment==		==Treatment==
	Treatment for rachischisis typically involves surgery to close the spinal opening. This is usually performed within the first few days of life. Additional treatments may be needed to manage other symptoms and complications.		Treatment for rachischisis typically involves surgery to close the spinal opening. This is usually performed within the first few days of life. Additional treatments may be needed to manage other symptoms and complications.

	==Prognosis==		==Prognosis==
	The prognosis for individuals with rachischisis varies widely. Some individuals may have significant physical and intellectual disabilities, while others may have relatively mild symptoms.		The prognosis for individuals with rachischisis varies widely. Some individuals may have significant physical and intellectual disabilities, while others may have relatively mild symptoms.

	==See Also==		==See Also==
	* [[Spina Bifida]]		* [[Spina Bifida]]
	* [[Neural Tube Defects]]		* [[Neural Tube Defects]]
	* [[Folic Acid]]		* [[Folic Acid]]

	[[Category:Congenital Disorders]]		[[Category:Congenital Disorders]]
	[[Category:Neural Tube Defects]]		[[Category:Neural Tube Defects]]
	[[Category:Spina Bifida]]		[[Category:Spina Bifida]]

	{{stub}}		{{stub}}
	~~== Rachischisis ==~~
	~~<gallery>~~
	~~File:Craniorachischisis (mouse).png\|Craniorachischisis in mouse~~
	~~</gallery>~~

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	{{stub}}		{{stub}}
			== Rachischisis ==
			<gallery>
			File:Craniorachischisis (mouse).png\|Craniorachischisis in mouse
			</gallery>

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2024-02-25T17:37:11Z

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New page

'''Rachischisis''' is a severe form of [[Spina Bifida|spina bifida]] in which the [[vertebral arch]]es and [[neural tube]] fail to close, resulting in an open spinal column. This condition is typically evident at birth and can lead to significant neurological complications.

==Etiology==
The exact cause of rachischisis is unknown, but it is believed to be a combination of genetic and environmental factors. Some studies suggest a link between the mother's diet during pregnancy, particularly a deficiency in [[Folic Acid|folic acid]], and the development of neural tube defects like rachischisis.

==Symptoms==
The most obvious symptom of rachischisis is a visible opening in the spine at birth. Other symptoms can include neurological problems, such as [[Paralysis|paralysis]] and [[Hydrocephalus|hydrocephalus]], as well as issues with bladder and bowel control.

==Diagnosis==
Rachischisis can often be diagnosed before birth through [[Ultrasound|ultrasound]] imaging. After birth, a physical examination of the newborn can confirm the diagnosis.

==Treatment==
Treatment for rachischisis typically involves surgery to close the spinal opening. This is usually performed within the first few days of life. Additional treatments may be needed to manage other symptoms and complications.

==Prognosis==
The prognosis for individuals with rachischisis varies widely. Some individuals may have significant physical and intellectual disabilities, while others may have relatively mild symptoms.

==See Also==
* [[Spina Bifida]]
* [[Neural Tube Defects]]
* [[Folic Acid]]

[[Category:Congenital Disorders]]
[[Category:Neural Tube Defects]]
[[Category:Spina Bifida]]

{{stub}}

Rachischisis - Revision history

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