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<p><b>New page</b></p><div>'''RECQL4''' is a gene that provides instructions for making a protein that is involved in maintaining the stability of a cell's genetic information. This protein is a member of the RecQ helicase family, a group of proteins that unwind the double helix of DNA. The RECQL4 protein is thought to play a critical role in DNA replication and repair.<br />
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== Function ==<br />
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The RECQL4 protein is involved in several important cellular activities. It helps to regulate the process of copying (replicating) DNA in preparation for cell division. The protein also plays a role in repairing damaged DNA and maintaining the structure of chromosomes, the structures that hold DNA.<br />
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== Clinical significance ==<br />
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Mutations in the RECQL4 gene are associated with three rare, overlapping conditions known as [[Rothmund-Thomson syndrome]], [[Rapadilino syndrome]], and [[Ballard syndrome]]. These conditions have some features in common, including slow growth, skeletal abnormalities, and an increased risk of developing cancer. <br />
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== See also ==<br />
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* [[DNA helicase]]<br />
* [[DNA replication]]<br />
* [[DNA repair]]<br />
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== References ==<br />
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<references /><br />
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== External links ==<br />
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* [https://ghr.nlm.nih.gov/gene/RECQL4 RECQL4] at [[Genetics Home Reference]]<br />
* [https://www.ncbi.nlm.nih.gov/gene/9401 RECQL4] at [[National Center for Biotechnology Information]]<br />
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[[Category:Genes]]<br />
[[Category:DNA repair]]<br />
[[Category:DNA replication]]<br />
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