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<p>CSV import</p> <p><b>New page</b></p><div>{{Short description|Chemical compound}}<br /> {{Drugbox<br /> | verifiedfields = changed<br /> | verifiedrevid = 477241123<br /> | IUPAC_name = 1-(2,3-dihydro-1H-inden-2-yl)-4-(3-chlorophenyl)piperazine<br /> | image = Spirochlorphine.svg<br /> | image_size = 200px<br /> | image_alt = Structural formula of R6890<br /> | width = <br /> | alt = <br /> | caption = Chemical structure of R6890<br /> | CAS_number = 119192-32-4<br /> | PubChem = 65880<br /> | ChemSpiderID = 59292<br /> | UNII = 0X9U3V0A7M<br /> | KEGG = D05892<br /> | ChEMBL = 2104010<br /> | C=19<br /> | H=22<br /> | Cl=1<br /> | N=2<br /> | smiles = Clc1cccc(c1)N2CCN(CC2)C3Cc4ccccc4C3<br /> }}<br /> <br /> &#039;&#039;&#039;R6890&#039;&#039;&#039; is a chemical compound that has been studied for its potential pharmacological properties. It is known for its action as a selective [[serotonin receptor]] antagonist, particularly targeting the [[5-HT2A receptor]].<br /> <br /> ==Chemical Structure==<br /> [[File:Spirochlorphine.svg|Chemical structure of R6890|thumb|right]]<br /> R6890 is chemically classified as a piperazine derivative. Its IUPAC name is 1-(2,3-dihydro-1H-inden-2-yl)-4-(3-chlorophenyl)piperazine. The compound features a piperazine ring, which is a common motif in many pharmacologically active compounds, linked to a chlorophenyl group and an indanyl moiety.<br /> <br /> ==Pharmacology==<br /> R6890 acts primarily as a selective antagonist at the [[5-HT2A receptor]], a subtype of the [[serotonin receptor]] family. This receptor is implicated in various neurological processes, including mood regulation, perception, and cognition. By blocking this receptor, R6890 may influence these processes, although its precise effects in humans are not fully understood.<br /> <br /> ==Potential Applications==<br /> The selective antagonism of the 5-HT2A receptor by R6890 suggests potential applications in the treatment of disorders such as [[schizophrenia]], [[depression]], and other conditions where serotonin dysregulation is a factor. However, further research is necessary to fully elucidate its therapeutic potential and safety profile.<br /> <br /> ==Research and Development==<br /> R6890 has been the subject of various preclinical studies to assess its pharmacological properties and potential therapeutic uses. These studies typically involve in vitro assays and animal models to determine its efficacy and safety.<br /> <br /> ==Related Compounds==<br /> R6890 is related to other piperazine derivatives that also target serotonin receptors. These compounds are often explored for their potential in treating psychiatric and neurological disorders.<br /> <br /> ==Related Pages==<br /> * [[Serotonin receptor]]<br /> * [[5-HT2A receptor]]<br /> * [[Piperazine]]<br /> * [[Pharmacology]]<br /> <br /> [[Category:Serotonin antagonists]]<br /> [[Category:Piperazines]]<br /> [[Category:Experimental drugs]]</div>

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