https://wikimd.org/index.php?action=history&feed=atom&title=Pyruvate_decarboxylation 2026-05-12T22:07:32Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Pyruvate_decarboxylation&diff=6347075&oldid=prev 2025-02-25T20:51:17Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:51, 25 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l13">Line 13:</td> <td colspan="2" class="diff-lineno">Line 13:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biochemistry-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biochemistry-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Pyruvate_decarboxylation ==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;gallery&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Pyruvate_dehydrogenase_complex_reaction.svg|Pyruvate dehydrogenase complex reaction</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=Pyruvate_decarboxylation&diff=5451279&oldid=prev 2024-03-25T02:50:31Z

<p>CSV import</p> <p><b>New page</b></p><div>{{png-image}}<br /> &#039;&#039;&#039;Pyruvate decarboxylation&#039;&#039;&#039; is a chemical [[reaction]] that represents a key step in the [[metabolic pathway]] known as [[glycolysis]]. During this process, pyruvate molecules, which are the end products of glycolysis, are converted into acetyl-CoA, a crucial intermediate in [[metabolism]]. This reaction is catalyzed by the [[enzyme]] complex known as pyruvate dehydrogenase complex (PDC).<br /> <br /> The conversion of pyruvate into acetyl-CoA is significant for several reasons. Firstly, it links the glycolytic pathway with the [[Citric Acid Cycle]] (also known as the Krebs cycle or TCA cycle), allowing for the efficient production of [[ATP]] (adenosine triphosphate), which is the energy currency of the cell. Secondly, it provides acetyl-CoA for [[fatty acid synthesis]] and [[amino acid synthesis]], which are essential for the biosynthesis of important biomolecules.<br /> <br /> The reaction involves the decarboxylation of pyruvate, which means a carboxyl group is removed from pyruvate in the form of carbon dioxide. The remaining two-carbon fragment is then attached to Coenzyme A (CoA) to form acetyl-CoA. This process is facilitated by several cofactors, including thiamine pyrophosphate (TPP), lipoic acid, FAD (flavin adenine dinucleotide), and NAD+ (nicotinamide adenine dinucleotide).<br /> <br /> The pyruvate dehydrogenase complex itself is highly regulated, with its activity being modulated by the levels of its substrates and products, as well as by phosphorylation and dephosphorylation. This ensures that the flow of carbon from glucose to ATP production is efficiently managed according to the cell&#039;s energy needs.<br /> <br /> [[Category:Biochemistry]]<br /> [[Category:Metabolic pathways]]<br /> [[Category:Enzymes]]<br /> <br /> {{biochemistry-stub}}</div>

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