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2024-03-05T23:58:07Z

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[[File:Propylketobemidone.svg|thumb|{{PAGENAME}}]] <br>'''Propylketobemidone''' is a [[synthetic opioid]] that is chemically related to [[ketobemidone]]. It was developed in the 1950s during research into analogues of [[pethidine]] and was assessed by the United Nations Office on Drugs and Crime but was not included on the list of drugs under international control, probably because it was not used in medicine or veterinary medicine.

==Chemistry==

Propylketobemidone is a [[ketone]] and is related to other drugs such as [[ketobemidone]] and [[pethidine]]. It is more potent than pethidine and has similar effects to other opioids. Propylketobemidone has a [[methyl group]] at the 3 position on the piperidine ring, which is the same place where the methyl group is located in ketobemidone.

==Pharmacology==

As an [[opioid]], propylketobemidone acts on the [[mu-opioid receptor]] in the brain and spinal cord, which are the main sites of action for the most commonly used opioids. Activation of the mu-opioid receptor is responsible for the analgesic effects of opioids. Like other opioids, propylketobemidone can cause [[respiratory depression]], [[constipation]], and [[dependence]].

==Legal status==

Propylketobemidone is not currently under international control. The United Nations Office on Drugs and Crime has assessed propylketobemidone but did not include it on the list of substances under international control, probably because it is not used in medicine or veterinary medicine.

==See also==

* [[Ketobemidone]]
* [[Pethidine]]
* [[Opioid]]

[[Category:Opioids]]
[[Category:Ketones]]
[[Category:Synthetic opioids]]
{{Opioid-stub}}
{{Pharmacology-stub}}

Propylketobemidone - Revision history

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