Propranolol - Revision history

Prab at 03:32, 22 March 2025

2025-03-22T03:32:22Z

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 A medication used to treat high blood pressure ("beta blocker").
 {{intro}}
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 [[Category:Sodium channel blockers]]
 [[Category:1-Naphthyl compounds]]

Prab: CSV import

2025-02-20T01:29:12Z

CSV import

← Older revision		Revision as of 01:29, 20 February 2025
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	[[Category:1-Naphthyl compounds]]		[[Category:1-Naphthyl compounds]]
	== Propranolol ==		== Propranolol ==
			<gallery>
			File:Propranolol.svg\|Propranolol
			File:Propranolol-from-1977-crystal-structure-3D-balls-side.png\|Propranolol 3D Structure
			File:Propranolol 80mg.png\|Propranolol 80mg
			File:Propranolol tablets.png\|Propranolol Tablets
			File:Propranolol hci sandoz 10mg.jpg\|Propranolol HCI Sandoz 10mg
			</gallery>
	<gallery>		<gallery>
	File:Propranolol.svg\|Propranolol		File:Propranolol.svg\|Propranolol

Prab: CSV import

2025-02-20T01:26:13Z

CSV import

← Older revision		Revision as of 01:26, 20 February 2025
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	[[Category:Sodium channel blockers]]		[[Category:Sodium channel blockers]]
	[[Category:1-Naphthyl compounds]]		[[Category:1-Naphthyl compounds]]
			== Propranolol ==
			<gallery>
			File:Propranolol.svg\|Propranolol
			File:Propranolol-from-1977-crystal-structure-3D-balls-side.png\|Propranolol 3D Structure
			File:Propranolol 80mg.png\|Propranolol 80mg
			File:Propranolol tablets.png\|Propranolol Tablets
			File:Propranolol hci sandoz 10mg.jpg\|Propranolol HCI Sandoz 10mg
			</gallery>

Prab at 02:38, 17 January 2025

2025-01-17T02:38:47Z

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-[[File:Propranolol.svg|thumb|Propranolol]]
+{{Drugbox
 A medication used to treat high blood pressure ("beta blocker").
 {{intro}}
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 {{se}}
 Common side effects of propranolol include [[bradycardia]], hypotension, [[fatigue]], [[dizziness]], [[depression]], memory loss, [[incontinence]], cold limbs and less commonly severe hypotension, [[heart failure]] and bronchospasm. Sudden withdrawal can trigger rebound [[hypertension]]. Beta-blockers are contraindicated in patients with asthma, [[bradycardia]] and [[heart failure]] and should be used cautiously in the elderly and in patients with diabetes.
 {{beta blockers}}
 {{antihypertensives}}
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 {{Thyroid hormone receptor modulators}}
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 [[Category:5-HT1A antagonists]]
 [[Category:5-HT1B antagonists]]

Prab at 18:54, 1 April 2023

2023-04-01T18:54:52Z

New page

[[File:Propranolol.svg|thumb|Propranolol]]
A medication used to treat high blood pressure ("beta blocker").
{{intro}}
Propranolol is a nonselective beta-adrenergic receptor blocker (beta-blocker) that is widely used for the therapy of [[hypertension]], cardiac arrhythmias, angina pectoris and hyperthyroidism.
{{livtox}}
Propranolol has yet to be convincingly associated with clinically apparent liver injury and is often used in patients with liver disease and cirrhosis.
{{moa}}
Propranolol (proe pran' oh lol) was the prototype beta-blocker developed for therapy of [[hypertension]] and is considered nonselective, acting on both the beta-1 and beta-2 adrenergic receptors. Beta-1 adrenergic blockade reduces the heart rate and myocardial contractility by slowing AV conduction and suppressing automaticity. Beta-2 blockade also affects peripheral vascular resistance and can cause bronchospasm and hypoglycemia. The beta-2 blockade is responsible for the majority of adverse effects associated with propranolol.
{{fda}}
Propranolol was approved for use in the United States in 1967 and is still commonly used, with several million prescriptions filled yearly. Propranolol is indicated for the management of [[hypertension]], myocardial infarction, angina pectoris, idiopathic hypertrophic subaortic stenosis and prevention of migraine and vascular [[headaches]]. Propranolol is also used to treat essential tremor, to decrease the heart rate in patients with hyperthyroidism, and to prevent recurrent variceal hemorrhage.
{{fda}}
Propranolol is available in multiple generic forms and under the trade name of Inderal in tablets of 10, 20, 40, 60, 80 and 90 mg, as well as extended or sustained release capsules of 60, 80, 120 and 160 mg. Liquid formulations for oral and parenteral administration are also available. The typical dose of propranolol in adults is 60 to 240 mg daily in 2 divided doses (one with extended release formulations), with subsequent dose modification based upon efficacy and tolerance.
{{se}}
Common side effects of propranolol include [[bradycardia]], hypotension, [[fatigue]], [[dizziness]], [[depression]], memory loss, [[incontinence]], cold limbs and less commonly severe hypotension, [[heart failure]] and bronchospasm. Sudden withdrawal can trigger rebound [[hypertension]]. Beta-blockers are contraindicated in patients with asthma, [[bradycardia]] and [[heart failure]] and should be used cautiously in the elderly and in patients with diabetes.
{{coststubd}}}
{{beta blockers}}
{{antihypertensives}}
{{Anxiolytics}}
{{Navboxes
| title = [[Pharmacodynamics]]
| titlestyle = background:#ccccff
| list1 =
{{Adrenergic receptor modulators}}
{{Ion channel modulators}}
{{Serotonin receptor modulators}}
{{Sigma receptor modulators}}
{{Thyroid hormone receptor modulators}}
}}
[[Category:5-HT1A antagonists]]
[[Category:5-HT1B antagonists]]
[[Category:5-HT2B antagonists]]
[[Category:AstraZeneca brands]]
[[Category:Anxiolytics]]
[[Category:Beta blockers]]
[[Category:Disulfiram-like drugs]]
[[Category:Isopropylamino compounds]]
[[Category:N-isopropyl-phenoxypropanolamines]]
[[Category:Naphthol ethers]]
[[Category:Norepinephrine reuptake inhibitors]]
[[Category:Scottish inventions]]
[[Category:Sodium channel blockers]]
[[Category:1-Naphthyl compounds]]