https://wikimd.org/index.php?action=history&feed=atom&title=Prasterone_sulfatePrasterone sulfate - Revision history2026-04-26T18:05:53ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Prasterone_sulfate&diff=6310186&oldid=prevPrab: CSV import2025-02-18T01:03:14Z<p>CSV import</p>
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</table>Prabhttps://wikimd.org/index.php?title=Prasterone_sulfate&diff=5167842&oldid=prevPrab: CSV import2024-02-19T23:25:21Z<p>CSV import</p>
<p><b>New page</b></p><div>'''Prasterone sulfate''' (also known as '''DHEA-S''') is a [[steroid]] [[hormone]] produced in the [[adrenal gland]]. It is the most abundant circulating steroid in the human body and plays a crucial role in a variety of physiological processes.<br />
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==Etymology==<br />
The term "Prasterone sulfate" is derived from the chemical name for the compound, pregnenolone sulfate. The prefix "pra-" is derived from the Latin "prae-", meaning "before", and "sterone" is derived from "steroid", referring to the class of compounds to which it belongs. The suffix "-sulfate" refers to the presence of a sulfate group in the molecule.<br />
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==Biochemistry==<br />
Prasterone sulfate is synthesized from [[cholesterol]] in the adrenal glands and is then converted into other hormones such as [[estrogen]] and [[testosterone]]. It is a precursor to these hormones, meaning that it is converted into them in the body. The conversion of prasterone sulfate into these hormones is regulated by the [[enzyme]]s [[sulfatase]] and [[sulfotransferase]].<br />
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==Physiological role==<br />
Prasterone sulfate plays a key role in a variety of physiological processes. It is involved in the regulation of [[immune system]] function, [[bone]] health, [[cardiovascular]] health, and [[brain]] function. It also plays a role in the body's response to [[stress]] and in the regulation of [[metabolism]].<br />
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==Clinical significance==<br />
Abnormal levels of prasterone sulfate in the body can be associated with a variety of medical conditions. High levels can be seen in conditions such as [[polycystic ovary syndrome]] and [[adrenal hyperplasia]], while low levels can be associated with conditions such as [[Addison's disease]] and [[hypopituitarism]]. Prasterone sulfate levels can also be affected by age, with levels typically decreasing as a person gets older.<br />
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==See also==<br />
* [[Dehydroepiandrosterone]]<br />
* [[Steroid hormone]]<br />
* [[Adrenal gland]]<br />
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==References==<br />
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[[Category:Endocrinology]]<br />
[[Category:Steroid hormones]]<br />
[[Category:Biochemistry]]<br />
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