https://wikimd.com/index.php?action=history&feed=atom&title=Pramipexole Pramipexole - Revision history 2026-04-23T22:16:45Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Pramipexole&diff=6318563&oldid=prev Prab: CSV import 2025-02-18T04:45:01Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:45, 18 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l19">Line 19:</td> <td colspan="2" class="diff-lineno">Line 19:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{coststubd}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{coststubd}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Pramipexole ==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;gallery&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Pramipexole.svg|Chemical structure of Pramipexole</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Pramipexole_ball-and-stick_model.png|Ball-and-stick model of Pramipexole</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Pramipexole.er.4.5mg.jpg|Pramipexole extended-release 4.5 mg tablets</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Pramipexole02point5mgAUCinfinity.png|Pharmacokinetic profile of Pramipexole 0.25 mg</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=Pramipexole&diff=88580&oldid=prev Prab at 15:48, 2 May 2019 2019-05-02T15:48:08Z <p></p> <p><b>New page</b></p><div>{{intro}}<br /> Pramipexole is a selective dopamine receptor agonist used in the therapy of [[Parkinson disease]].  <br /> <br /> {{livtox}}<br /> Pramipexole therapy is associated with a low rate of transient serum enzyme elevations during treatment, but has not been implicated in cases of clinically apparent acute liver injury.<br /> <br /> {{moa}}<br /> Pramipexole (pram&quot; i pex&#039; ole) is synthetic, nonergot derivative and dopamine receptor agonist that has selective activity for the D2 class of dopamine receptors and little agonist activity for the D1 class.  For this reason, pramipexole may be better tolerated than bromocriptine or pergolide which have activity for both D1 and D2 receptors.  Pramipexole was approved for use in the United States in 1997 for the therapy of symptomatic [[Parkinson disease]].  <br /> <br /> {{dose}}<br /> Pramipexole is available in tablets of 0.125, 0.25, 0.5, 1 and 1.5 mg generically and under the brand name of Miraplex.  It is used often, but not always in combination with levodopa/carbidopa.  Pramipexole is typically initiated in low doses (0.375 mg in 3 divided doses daily), with adjustment upwards based upon tolerance and clinical effects.  The typical maintenance dose for [[Parkinson disease]] is 1.5 to 4.5 mg daily in three divided doses.  Pramipexole can be initiated more quickly than bromocriptine or pergolide, and does not cause the profound hypotension and [[nausea]] that are typical of the ergot derivatives. <br /> <br /> == Use in [[Restless leg syndrome]] ==<br /> {{PAGENAME}} is also use in treating [restless leg syndrome]].<br /> <br /> {{se}}<br /> Common side effects include somnolence, fatigue, vivid dreams, anxiety, [[confusion]], depression, dizziness, headache and gastrointestinal upset.<br /> {{antiparkinson agents}}<br /> <br /> {{coststubd}}</div> Prab