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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Pozelimab</id>
	<title>Pozelimab - Revision history</title>
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	<updated>2026-04-25T14:57:38Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.org/index.php?title=Pozelimab&amp;diff=6518166&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Pozelimab&amp;diff=6518166&amp;oldid=prev"/>
		<updated>2025-03-17T23:33:39Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:33, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l39&quot;&gt;Line 39:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Pozelimab&amp;diff=6278227&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Pozelimab&amp;diff=6278227&amp;oldid=prev"/>
		<updated>2025-02-11T05:03:12Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 05:03, 11 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l38&quot;&gt;Line 38:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Pozelimab&amp;diff=5880362&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Pozelimab&amp;diff=5880362&amp;oldid=prev"/>
		<updated>2024-06-01T22:38:13Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Pozelimab&amp;#039;&amp;#039;&amp;#039; is a [[monoclonal antibody]] designed for the treatment of various [[autoimmune diseases]]. It is a fully human antibody that targets the complement protein C5, which plays a crucial role in the activation of the [[complement system]], a part of the [[immune system]].&lt;br /&gt;
&lt;br /&gt;
==Mechanism of Action==&lt;br /&gt;
Pozelimab works by binding to the C5 protein, inhibiting its cleavage into C5a and C5b. This inhibition prevents the formation of the [[membrane attack complex]] (MAC), which is responsible for cell lysis and inflammation in autoimmune conditions. By blocking this pathway, pozelimab reduces the inflammatory response and tissue damage associated with these diseases.&lt;br /&gt;
&lt;br /&gt;
==Clinical Applications==&lt;br /&gt;
Pozelimab is being investigated for its potential use in treating several autoimmune diseases, including:&lt;br /&gt;
* [[Paroxysmal nocturnal hemoglobinuria]] (PNH)&lt;br /&gt;
* [[Atypical hemolytic uremic syndrome]] (aHUS)&lt;br /&gt;
* [[Myasthenia gravis]]&lt;br /&gt;
* [[Neuromyelitis optica spectrum disorder]] (NMOSD)&lt;br /&gt;
&lt;br /&gt;
==Development and Approval==&lt;br /&gt;
Pozelimab is currently undergoing clinical trials to evaluate its safety and efficacy. The results of these trials will determine its potential approval by regulatory agencies such as the [[Food and Drug Administration]] (FDA) and the [[European Medicines Agency]] (EMA).&lt;br /&gt;
&lt;br /&gt;
==Side Effects==&lt;br /&gt;
As with other monoclonal antibodies, pozelimab may cause side effects, including:&lt;br /&gt;
* [[Infusion reactions]]&lt;br /&gt;
* [[Infections]]&lt;br /&gt;
* [[Headache]]&lt;br /&gt;
* [[Nausea]]&lt;br /&gt;
&lt;br /&gt;
Patients receiving pozelimab should be monitored for these adverse effects and managed accordingly.&lt;br /&gt;
&lt;br /&gt;
==Related Pages==&lt;br /&gt;
* [[Monoclonal antibody]]&lt;br /&gt;
* [[Autoimmune disease]]&lt;br /&gt;
* [[Complement system]]&lt;br /&gt;
* [[Paroxysmal nocturnal hemoglobinuria]]&lt;br /&gt;
* [[Atypical hemolytic uremic syndrome]]&lt;br /&gt;
* [[Myasthenia gravis]]&lt;br /&gt;
* [[Neuromyelitis optica spectrum disorder]]&lt;br /&gt;
&lt;br /&gt;
==Categories==&lt;br /&gt;
[[Category:Monoclonal antibodies]]&lt;br /&gt;
[[Category:Autoimmune diseases]]&lt;br /&gt;
[[Category:Immunology]]&lt;br /&gt;
&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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