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2025-02-17T02:03:32Z

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			File:Posaconazole.svg
			File:Posaconazole3d.png
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Prab: Created page with "{{intro}} Posaconazole is a potent triazole antifungal agent used in the prevention of invasive fungal infections due to aspergillosis and candida in high risk patient..."

2019-04-26T19:57:56Z

Created page with "{{intro}} Posaconazole is a potent triazole antifungal agent used in the prevention of invasive fungal infections due to aspergillosis and candida in high risk patient..."

New page

{{intro}}
Posaconazole is a potent triazole antifungal agent used in the prevention of invasive [[fungal infections]] due to [[aspergillosis]] and candida in high risk patients.

{{livtox}}
Posaconazole therapy is associated with transient, asymptomatic serum aminotransferase elevations and is a suspected but rare cause of clinically apparent acute drug induced liver injury.

{{moa}}
Posaconazole (poe" sa kon' a zole) is a synthetic triazole that is believed to act through inhibition of the fungal 14a-ergosterol demethylase, which is responsible for converting lanosterol to ergosterol and which blocks cell membrane synthesis. Posaconazole is active against a broad spectrum of fungal agents including Candida albicans and Aspergillus fumigatus.

{{fda}}
{{PAGENAME}} was approved for use in the United States in 2006. Current indications are oropharyngeal [[candidiasis]] and prophylaxis against invasive [[fungal infections]] in neutropenic or immunosuppressed patients.

{{dose}}
Posaconazole is available as a 100 mg delayed-release tablet and as an oral suspension of 40 mg/mL under the brand name Noxafil. A loading dose is recommended followed by maintenance doses of 100 to 300 mg daily; however, the dosage varies depending upon indications and the formulation used.

{{se}}
Common side effects include [[nausea]], [[vomiting]], [[diarrhea]], abdominal pain, [[headache]], [[dizziness]] and [[rash]].
{{antifungals}}
{{coststubd}}

Posaconazole - Revision history

Prab: CSV import

Prab: Created page with "{{intro}} Posaconazole is a potent triazole antifungal agent used in the prevention of invasive fungal infections due to aspergillosis and candida in high risk patient..."