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Poorly differentiated thyroid cancer - Revision history
2026-04-27T04:56:35Z
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2025-03-17T23:19:20Z
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2025-02-10T22:37:02Z
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2024-02-25T01:02:54Z
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<p><b>New page</b></p><div>{{Infobox medical condition (new)<br />
| name = Poorly differentiated thyroid carcinoma<br />
| synonyms = PDTC<br />
| image = <br />
| caption = <br />
| pronounce = <br />
| field = <br />
| symptoms = <br />
| complications = <br />
| onset = <br />
| duration = <br />
| types = <br />
| causes = <br />
| risks = <br />
| diagnosis = <br />
| differential = <br />
| prevention = <br />
| treatment = <br />
| medication = <br />
| prognosis = <br />
| frequency = <br />
| deaths = <br />
}}<br />
<br />
'''Poorly differentiated thyroid carcinoma''' is malignant neoplasm of follicular cell origin showing intermediate histopathological patterns between differentiated and undifferentiated [[thyroid cancer]]s.<ref>{{cite journal | vauthors=Volante M, Collini P, Nikiforov YE, Sakamoto A, Kakudo K, Katoh R, Lloyd RV, LiVolsi VA, Papotti M, Sobrinho-Simoes M, Bussolati G, Rosai J | title=Poorly differentiated thyroid carcinoma: the Turin proposal for the use of uniform diagnostic criteria and an algorithmic diagnostic approach. | journal=Am J Surg Pathol | year=2007 | pages=1256–64 | volume=31 | pmid=17667551 |doi=10.1097/PAS.0b013e3180309e6a | issue=8}}</ref><br />
==Histopathology==<br />
*Presence of small cells with round nuclei and scant cytoplasm with a diffuse solid pattern<br />
*Round or oval nests (insulae) or in trabeculae. <br />
*Solid growth and presence of microfollicles, some of which contain dense colloid.<br />
*Extrathyroidal extension and blood vessel invasion <br />
*Foci of necrosis, <br />
* Larger than 5&nbsp;cm in greatest diameter at diagnosis<br />
==Epidemiology==<br />
*PDTC affects predominantly females about 55 years of age<br />
<br />
==References==<br />
{{reflist}}<br />
== External links ==<br />
{{Medical resources<br />
| DiseasesDB = <br />
| ICD10 = {{ICD10|C|73||c|73}} <br />
| ICD9 = {{ICD9|193}} <br />
| ICDO = <br />
| OMIM = <br />
| MedlinePlus = <br />
| eMedicineSubj = med <br />
| eMedicineTopic = <br />
| MeshID = D013964 <br />
}}<br />
{{Endocrine gland neoplasia}}<br />
<br />
[[Category:Thyroid cancer]]<br />
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<br />
{{Oncology-stub}}<br />
{{dictionary-stub1}}</div>
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