https://wikimd.com/index.php?action=history&feed=atom&title=Polyketide Polyketide - Revision history 2026-04-23T23:35:24Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Polyketide&diff=6320992&oldid=prev Prab: CSV import 2025-02-18T10:56:11Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 10:56, 18 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l25">Line 25:</td> <td colspan="2" class="diff-lineno">Line 25:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{pharmacology-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{pharmacology-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{microbiology-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{microbiology-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== Polyketide ==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;gallery&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Orsellinsäure_is.svg|Orsellinsäure structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Biosynthesis_of_carminic_acid.jpg|Biosynthesis of carminic acid</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Geldanamycin.svg|Geldanamycin structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Doxycycline.svg|Doxycycline structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Erythromycin_A.svg|Erythromycin A structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:(–)-Aflatoxin_B1_Structural_Formulae_V.1.svg|Aflatoxin B1 structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table> Prab https://wikimd.com/index.php?title=Polyketide&diff=5370713&oldid=prev Prab: CSV import 2024-03-06T20:14:27Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Polyketide&#039;&#039;&#039; is a class of secondary metabolites produced by certain living organisms. Polyketides are synthesized by the polymerization of acetyl and propionyl subunits by a process that is similar to [[fatty acid]] synthesis. <br /> <br /> == Overview ==<br /> <br /> Polyketides are a large family of naturally occurring molecules that have diverse structures and functions. They are produced by bacteria, fungi, plants, and animals. They have a wide range of biological activities and pharmacological properties, including antibiotic, antifungal, antiviral, anticancer, immunosuppressive, and cholesterol-lowering activities. <br /> <br /> == Biosynthesis ==<br /> <br /> Polyketides are synthesized by polyketide synthases (PKSs), which are large multi-enzyme complexes. PKSs are classified into three types: type I, type II, and type III. Type I PKSs are large, multifunctional proteins that contain all of the enzymatic activities necessary for polyketide biosynthesis in a single polypeptide chain. Type II PKSs are composed of separate, monofunctional proteins that each perform one step in the biosynthesis process. Type III PKSs are homodimeric proteins that can use a variety of coenzyme A-linked extender units to synthesize a diverse array of polyketides.<br /> <br /> == Biological significance ==<br /> <br /> Polyketides have a wide range of biological activities and are used as pharmaceuticals, agrochemicals, and veterinary drugs. They are also important research tools in cell biology and biochemistry. Some well-known polyketides include the antibiotic [[erythromycin]], the cholesterol-lowering drug [[lovastatin]], and the anticancer drug [[doxorubicin]].<br /> <br /> == See also ==<br /> <br /> * [[Nonribosomal peptide]]<br /> * [[Terpenoid]]<br /> * [[Natural product]]<br /> <br /> [[Category:Biochemistry]]<br /> [[Category:Pharmacology]]<br /> [[Category:Microbiology]]<br /> {{biochemistry-stub}}<br /> {{pharmacology-stub}}<br /> {{microbiology-stub}}</div> Prab