https://wikimd.com/index.php?action=history&feed=atom&title=Polyestriol_phosphate 2026-04-23T12:46:50Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.com/index.php?title=Polyestriol_phosphate&diff=6309209&oldid=prev 2025-02-18T00:46:10Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 00:46, 18 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l37">Line 37:</td> <td colspan="2" class="diff-lineno">Line 37:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><br></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;gallery&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Polyestriol_phosphate.svg|Polyestriol phosphate structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Estriol_phosphate_molecule_ball.png|Estriol phosphate molecule model</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table>

Prab https://wikimd.com/index.php?title=Polyestriol_phosphate&diff=5360087&oldid=prev 2024-03-04T16:16:02Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Polyestriol phosphate&#039;&#039;&#039; is a [[synthetic]], [[steroidal]] [[estrogen]] and an [[estrogen ester]] – specifically, the 3-(dihydrogen phosphate) ester of [[polyestriol]] – which is used in [[medicine]]. It is a long-acting and [[water-soluble]] form of [[polyestriol]].<br /> <br /> ==Pharmacology==<br /> <br /> As a [[phosphate]] ester of [[polyestriol]], polyestriol phosphate is a [[prodrug]] of [[polyestriol]] that is stored in the body and is slowly [[hydrolyzed]] into [[polyestriol]], which is the active form. The medication has a very long [[duration of action]] when given by [[intramuscular injection]], and a single dose has a duration of about one month.<br /> <br /> ==Medical uses==<br /> <br /> Polyestriol phosphate is used in the treatment of [[menopausal symptoms]] and [[osteoporosis]] in women. It has also been used to treat [[prostate cancer]] in men.<br /> <br /> ==Side effects==<br /> <br /> Side effects of polyestriol phosphate are similar to those of other [[estrogens]] and include [[breast tenderness]], [[breast enlargement]], [[nausea]], [[headache]], and [[fluid retention]].<br /> <br /> ==Pharmacokinetics==<br /> <br /> Following an [[intramuscular injection]] of polyestriol phosphate, the medication is slowly [[absorbed]] into the [[bloodstream]] and is then slowly [[hydrolyzed]] into [[polyestriol]], which is the active form.<br /> <br /> ==History==<br /> <br /> Polyestriol phosphate was first described in the literature in 1957 and was introduced for medical use by 1960.<br /> <br /> ==See also==<br /> * [[List of estrogen esters]]<br /> * [[List of estrogens]]<br /> <br /> {{Estrogenics}}<br /> {{Prodrugs}}<br /> {{Estrogen esters}}<br /> {{Estrogens}}<br /> <br /> [[Category:Estrogens]]<br /> [[Category:Prodrugs]]<br /> [[Category:Phosphate esters]]<br /> [[Category:Synthetic estrogens]]<br /> [[Category:Estrogen esters]]<br /> <br /> {{medicine-stub}}</div>

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