Poikiloderma - Revision history

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	[[Category:Genetic disorders]]		[[Category:Genetic disorders]]
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			<gallery>
			File:Rothmund-Thomson_syndrome.jpg\|Rothmund-Thomson syndrome
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	{{Infobox medical condition ~~(new)~~
	\| name = <!--~~{{PAGENAME}} by default~~-->		{{Infobox medical condition
	\| ~~synonym~~ =		\| name = Poikiloderma
	~~\| image = File:Rothmund~~-~~Thomson syndrome.jpg~~		\| image = <!-- Image removed -->
	\| ~~image_size~~ =		\| caption = <!-- Caption removed -->
	\| ~~alt~~ =		\| field = [[Dermatology]]
	~~\| caption = People with varying manifestations of poikiloderma~~		\| synonyms =
	~~\| pronounce =~~		\| symptoms = [[Skin atrophy]], [[telangiectasia]], [[hyperpigmentation]], [[hypopigmentation]]
	~~\| specialty = dermatology~~		\| complications =
	\| symptoms =		\| onset =
	\| complications =		\| duration =
	\| onset =		\| causes = [[Genetic disorders]], [[environmental factors]]
	\| duration =		\| risks =
	~~\| types~~ =		\| diagnosis = [[Clinical examination]], [[biopsy]]
	\| causes =		\| differential = [[Lupus erythematosus]], [[scleroderma]]
	\| risks =		\| treatment = [[Sun protection]], [[topical treatments]]
	\| diagnosis =		\| medication =
	\| differential =		\| prognosis =
	~~\| prevention~~ =		\| frequency =
	\| treatment =
	\| medication =
	\| prognosis =
	\| frequency =
	~~\| deaths~~ =
	}}		}}
	~~'''Poikiloderma''' is a skin condition that consists of areas of [[hypopigmentation]], [[hyperpigmentation]], [[telangiectasias]] and [[atrophy]].~~
	Poikiloderma of Civatte is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage.<ref>{{cite book\|last1=Raulin\|first1=Christian\|last2=Karsai\|first2=Syrus\|title=Laser and IPL Technology in Dermatology and Aesthetic Medicine\|date=2011\|publisher=Springer Science & Business Media\|isbn=9783642034381\|page=236\|url=https://books.google.com/?id=yY7fz5J4g4sC&dq=Poikiloderma+check+neck\|accessdate=7 March 2018\|language=en}}</ref>

	~~==Types==~~
	* [[Poikiloderma vasculare atrophicans]]
	* [[Poikiloderma of Civatte]]
	* [[Hereditary sclerosing poikiloderma]]

	~~==Causes==~~
	*Congenital
	~~#[[Rothmund-Thompson syndrome]]~~
	~~#[[Dyskeratosis congenita]]~~
	~~#[[Mendes da Costa syndrome]]~~

	*Other hereditary causes
	~~#[[Degos-Touraine syndrome]]~~
	~~#Diffuse and macular atrophic [[dermatosis]]~~
	~~#[[Hereditary sclerosing poikiloderma]] of weary~~
	~~#[[Kindler syndrome]]~~
	~~#[[Weary-Kindler syndrome]]~~
	~~#[[Xeroderma pigmentosum]]~~

	*Acquired		'''Poikiloderma''' is a condition characterized by changes in the skin, including [[atrophy]], [[telangiectasia]], and variations in pigmentation such as [[hyperpigmentation]] and [[hypopigmentation]]. It is often a result of [[genetic disorders]] or [[environmental factors]].
	~~#Injury to cold~~, ~~heat~~, ~~ionizing radiation, exposure to sensitizing chemicals~~
	#[[~~Lichen planus~~]]
	#[[~~Dermatomyositis~~]]
	#[[~~Lupus erythematosus~~]]
	#[[~~Systemic sclerosis~~]]
	#[[~~Cutaneous T cell lymphoma~~]]s

	==~~Pathogenesis~~==		== Signs and Symptoms ==
	~~The exact cause~~ of ~~poikiloderma~~ of ~~Civatte is unknown; however, extended sun exposure, namely~~ the [[~~ultraviolet light~~]] ~~emitted by~~ the ~~sun, is the primary factor.<ref>American Osteopathic College of Dermatology~~ [~~http://www.aocd.org/skin/dermatologic_diseases/Poikiloderma~~-of~~-Civatte.html "Dermatologic Disease Database"], ''aocd.org'', referenced July 22, 2011.</ref>~~		Poikiloderma presents with a combination of skin changes:
			* [[Skin atrophy]] - thinning of the skin
			* [[Telangiectasia]] - visible small blood vessels
			* [[Hyperpigmentation]] - darkening of the skin
			* [[Hypopigmentation]] - lightening of the skin

	==~~Diagnosis~~==		== Causes ==
	~~{{Empty section\|date=July 2018}}~~		The causes of poikiloderma can be varied and include:
			* [[Genetic disorders]] such as [[Rothmund-Thomson syndrome]], [[Bloom syndrome]], and [[Dyskeratosis congenita]].
			* [[Environmental factors]] like chronic sun exposure, which can lead to [[actinic damage]].

	==~~Treatment~~==		== Diagnosis ==
	~~Albeit difficult, treatment~~ of poikiloderma ~~of Civatte involves~~ the ~~delivery of multiple wavelengths~~ of ~~intense pulsed light (IPL) to~~ the ~~affected area~~.~~<ref>PubMed.gov~~ [~~https://www.ncbi.nlm.nih.gov/pubmed/11335804 "Treatment of poikiloderma of Civatte with an intense pulsed light source"~~]~~, ''PubMed.gov'', referenced July 22, 2011~~.~~</ref>~~		Diagnosis of poikiloderma is primarily clinical, based on the appearance of the skin. A [[biopsy]] may be performed to rule out other conditions and confirm the diagnosis.

	==~~See also~~==		== Differential Diagnosis ==
	* [[~~Osteopoikilosis~~]]		Conditions that may present similarly to poikiloderma include:
	* [[~~List of cutaneous conditions~~]]		* [[Lupus erythematosus]]
			* [[Scleroderma]]
			* [[Dermatomyositis]]

	==~~References~~==		== Treatment ==
	~~{{Reflist}}~~		Management of poikiloderma focuses on:
			* [[Sun protection]] to prevent further damage
			* [[Topical treatments]] such as [[retinoids]] or [[steroids]] to improve skin appearance

	{{pigmentation ~~disorders}}~~		== See Also ==
			* [[Dermatology]]
			* [[Genetic disorders]]
			* [[Skin pigmentation]]

	~~[[Category:Disturbances of human pigmentation]]~~		== References ==
			<references/>

			== External Links ==
			* [Poikiloderma at DermNet NZ](https://dermnetnz.org/topics/poikiloderma/)

	~~{{Cutaneous-condition-stub}}~~		[[Category:Dermatology]]
			[[Category:Genetic disorders]]
			[[Category:Skin conditions]]

Prab: 1 revision imported

2019-09-01T15:04:57Z

1 revision imported

New page

{{Infobox medical condition (new)
| name = 
| synonym =
| image = File:Rothmund-Thomson syndrome.jpg
| image_size =
| alt =
| caption = People with varying manifestations of poikiloderma
| pronounce =
| specialty = dermatology
| symptoms =
| complications =
| onset =
| duration =
| types =
| causes =
| risks =
| diagnosis =
| differential =
| prevention =
| treatment =
| medication =
| prognosis =
| frequency =
| deaths =
}}
'''Poikiloderma''' is a skin condition that consists of areas of [[hypopigmentation]], [[hyperpigmentation]], [[telangiectasias]] and [[atrophy]].
Poikiloderma of Civatte is most frequently seen on the chest or the neck, characterized by red colored pigment on the skin that is commonly associated with sun damage.<ref>{{cite book|last1=Raulin|first1=Christian|last2=Karsai|first2=Syrus|title=Laser and IPL Technology in Dermatology and Aesthetic Medicine|date=2011|publisher=Springer Science & Business Media|isbn=9783642034381|page=236|url=https://books.google.com/?id=yY7fz5J4g4sC&dq=Poikiloderma+check+neck|accessdate=7 March 2018|language=en}}</ref>

==Types==
* [[Poikiloderma vasculare atrophicans]]
* [[Poikiloderma of Civatte]]
* [[Hereditary sclerosing poikiloderma]]

==Causes==
*Congenital
#[[Rothmund-Thompson syndrome]]
#[[Dyskeratosis congenita]]
#[[Mendes da Costa syndrome]]

*Other hereditary causes
#[[Degos-Touraine syndrome]]
#Diffuse and macular atrophic [[dermatosis]]
#[[Hereditary sclerosing poikiloderma]] of weary
#[[Kindler syndrome]]
#[[Weary-Kindler syndrome]]
#[[Xeroderma pigmentosum]]

*Acquired
#Injury to cold, heat, ionizing radiation, exposure to sensitizing chemicals
#[[Lichen planus]]
#[[Dermatomyositis]]
#[[Lupus erythematosus]]
#[[Systemic sclerosis]]
#[[Cutaneous T cell lymphoma]]s

==Pathogenesis==
The exact cause of poikiloderma of Civatte is unknown; however, extended sun exposure, namely the [[ultraviolet light]] emitted by the sun, is the primary factor.<ref>American Osteopathic College of Dermatology [http://www.aocd.org/skin/dermatologic_diseases/Poikiloderma-of-Civatte.html "Dermatologic Disease Database"], ''aocd.org'', referenced July 22, 2011.</ref>

==Diagnosis==
{{Empty section|date=July 2018}}

==Treatment==
Albeit difficult, treatment of poikiloderma of Civatte involves the delivery of multiple wavelengths of intense pulsed light (IPL) to the affected area.<ref>PubMed.gov [https://www.ncbi.nlm.nih.gov/pubmed/11335804 "Treatment of poikiloderma of Civatte with an intense pulsed light source"], ''PubMed.gov'', referenced July 22, 2011.</ref>

==See also==
* [[Osteopoikilosis]]
* [[List of cutaneous conditions]]

==References==
{{Reflist}}

{{pigmentation disorders}}

[[Category:Disturbances of human pigmentation]]

{{Cutaneous-condition-stub}}