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	<id>https://wikimd.org/index.php?action=history&amp;feed=atom&amp;title=Pitrakinra</id>
	<title>Pitrakinra - Revision history</title>
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	<updated>2026-04-27T01:36:17Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
	<generator>MediaWiki 1.44.2</generator>
	<entry>
		<id>https://wikimd.org/index.php?title=Pitrakinra&amp;diff=6529130&amp;oldid=prev</id>
		<title>Prab at 17:38, 18 March 2025</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Pitrakinra&amp;diff=6529130&amp;oldid=prev"/>
		<updated>2025-03-18T17:38:00Z</updated>

		<summary type="html">&lt;p&gt;&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 17:38, 18 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Pitrakinra&amp;diff=6517692&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Pitrakinra&amp;diff=6517692&amp;oldid=prev"/>
		<updated>2025-03-17T23:05:11Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 23:05, 17 March 2025&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Pitrakinra&amp;diff=6262137&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Pitrakinra&amp;diff=6262137&amp;oldid=prev"/>
		<updated>2025-02-10T22:40:45Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 22:40, 10 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l25&quot;&gt;Line 25:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.org/index.php?title=Pitrakinra&amp;diff=5167662&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.org/index.php?title=Pitrakinra&amp;diff=5167662&amp;oldid=prev"/>
		<updated>2024-02-19T23:12:33Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Pitrakinra&amp;#039;&amp;#039;&amp;#039; is a [[recombinant protein]] that is designed to be a selective antagonist of the [[interleukin-4 receptor]]. It is used in the treatment of [[asthma]] and [[allergic diseases]]. The drug was developed by [[Aerovance]], a biopharmaceutical company based in [[Berkeley, California]].&lt;br /&gt;
&lt;br /&gt;
==Etymology==&lt;br /&gt;
The name &amp;quot;Pitrakinra&amp;quot; is derived from the [[Greek language|Greek]] words &amp;quot;pitra&amp;quot;, meaning &amp;quot;against&amp;quot;, and &amp;quot;kinra&amp;quot;, meaning &amp;quot;movement&amp;quot;. This reflects the drug&amp;#039;s function as an antagonist, working against the movement of certain proteins in the body.&lt;br /&gt;
&lt;br /&gt;
==Mechanism of Action==&lt;br /&gt;
Pitrakinra works by binding to the interleukin-4 receptor, preventing the binding of [[interleukin-4]] and [[interleukin-13]], two cytokines that are involved in the inflammatory response in asthma and allergic diseases. By blocking these cytokines, Pitrakinra reduces inflammation and improves symptoms.&lt;br /&gt;
&lt;br /&gt;
==Clinical Trials==&lt;br /&gt;
Pitrakinra has been tested in several [[clinical trial|clinical trials]]. In a Phase II trial, the drug was found to significantly reduce asthma symptoms and improve lung function in patients with moderate to severe asthma. In another trial, Pitrakinra was found to be effective in reducing symptoms in patients with atopic dermatitis, a type of allergic skin disease.&lt;br /&gt;
&lt;br /&gt;
==Side Effects==&lt;br /&gt;
Common side effects of Pitrakinra include injection site reactions, upper respiratory tract infections, and headache. Serious side effects can include severe allergic reactions.&lt;br /&gt;
&lt;br /&gt;
==See Also==&lt;br /&gt;
* [[Interleukin-4 receptor]]&lt;br /&gt;
* [[Aerovance]]&lt;br /&gt;
* [[Recombinant protein]]&lt;br /&gt;
* [[Asthma]]&lt;br /&gt;
* [[Allergic diseases]]&lt;br /&gt;
&lt;br /&gt;
[[Category:Drugs]]&lt;br /&gt;
[[Category:Asthma]]&lt;br /&gt;
[[Category:Allergic diseases]]&lt;br /&gt;
[[Category:Recombinant proteins]]&lt;br /&gt;
{{stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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