https://wikimd.org/index.php?action=history&feed=atom&title=PethidinePethidine - Revision history2026-05-12T22:34:45ZRevision history for this page on the wikiMediaWiki 1.44.2https://wikimd.org/index.php?title=Pethidine&diff=6320115&oldid=prevPrab: CSV import2025-02-18T05:01:16Z<p>CSV import</p>
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<p><b>New page</b></p><div>'''Pethidine''' (also known as '''meperidine''' and sold under the brand name '''Demerol''' among others) is a [[synthetic opioid]] of the [[phenylpiperidine]] class. It is used to treat moderate to severe pain, and can also be used for anesthesia and for the treatment of [[shivering]]. Pethidine is less potent and has a shorter duration of action than [[morphine]]. It also has significant [[antimuscarinic]] effects.<br />
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==Pharmacology==<br />
Pethidine is a [[synthetic opioid]] that is used as an [[analgesic]]. It is less potent than [[morphine]] and has a shorter duration of action. Pethidine has significant [[antimuscarinic]] effects, which can lead to dry mouth, blurred vision, and urinary retention.<br />
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==Medical uses==<br />
Pethidine is used to treat moderate to severe pain. It can also be used for anesthesia and for the treatment of [[shivering]]. It is often used in the management of pain during labor and delivery, although there is evidence to suggest that it may delay the progress of labor.<br />
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==Side effects==<br />
Common side effects of pethidine include [[nausea]], [[vomiting]], [[dizziness]], and [[sedation]]. Less common side effects include [[respiratory depression]], [[hypotension]], and [[allergic reactions]]. Pethidine can also cause [[dependence]] and [[withdrawal symptoms]] if used for extended periods of time.<br />
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==Contraindications==<br />
Pethidine should not be used in patients with hypersensitivity to pethidine or to any other components of the formulation. It is also contraindicated in patients with severe respiratory depression, acute or severe bronchial asthma, or upper airway obstruction.<br />
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==See also==<br />
* [[Opioid]]<br />
* [[Analgesic]]<br />
* [[Morphine]]<br />
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[[Category:Opioids]]<br />
[[Category:Analgesics]]<br />
[[Category:Phenylpiperidines]]<br />
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