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	~~'''~~Pertechnetate''' is a [[chemical compound]] that is commonly used in [[nuclear medicine]] for diagnostic purposes. It is a [[technetium]] compound with the chemical formula TcO4−. Pertechnetate is a monovalent [[anion]] and is the most stable oxidation state of technetium. It is similar in chemical behavior to [[perchlorate]].		{{DISPLAYTITLE:Pertechnetate}}

	==~~Chemical Properties~~==		== Pertechnetate ==
	~~Pertechnetate is a strong~~ [[~~oxidizing agent~~]]. It is ~~soluble~~ in ~~water~~ and ~~its solutions are colorless~~. The ~~compound~~ is ~~stable in air. It can be reduced~~ to ~~technetium by~~ [[~~electrolysis~~]].		[[File:Pertechnetate1.svg\|thumb\|right\|150px\|Structure of the pertechnetate ion]]
			The '''pertechnetate''' ion is a chemical species with the formula '''TcO__'''. It is the most stable form of technetium in aqueous solution and is commonly encountered in the field of [[nuclear medicine]]. The pertechnetate ion is analogous to the [[permanganate]] ion, MnO__, and the [[perrhenate]] ion, ReO__, in terms of structure and charge.

	==~~Medical Uses~~==		== Properties ==
	~~In nuclear medicine~~, ~~pertechnetate is used as~~ a ~~[[radiopharmaceutical]]~~. It is ~~used~~ in the ~~diagnosis of several medical conditions~~, ~~including [[thyroid disease]], [[heart disease]], and [[cancer]]. Pertechnetate~~ is ~~also used in the [[scintigraphy]] of the [[salivary gland]] and in~~ the ~~[[Meckel's diverticulum]] scan~~.		Pertechnetate is a tetrahedral anion, meaning it has a central technetium atom surrounded by four oxygen atoms arranged in a tetrahedral geometry. This configuration is typical for high oxidation state metal oxoanions. The technetium in pertechnetate is in the +7 oxidation state, which is the highest oxidation state for technetium.

	~~==Production==~~		Pertechnetate is colorless and diamagnetic, and it is soluble in water. It is a weak oxidizing agent compared to permanganate, but it can still participate in redox reactions under certain conditions.
	Pertechnetate is ~~produced by the [[oxidation]] of technetium-99m~~, ~~a [[radioisotope]] of technetium~~. ~~The oxidation~~ is ~~usually carried out in an [[alkaline solution]] using [[chloramine-T]] as the~~ oxidizing agent.

	==~~Safety~~==		== Applications ==
	~~As a radioactive compound, pertechnetate must be handled with care. It should be~~ used ~~only by trained professionals~~ in a ~~controlled environment~~. The ~~compound~~ is ~~not suitable for use~~ in ~~patients who are pregnant or breastfeeding~~.		Pertechnetate is widely used in [[nuclear medicine]] as a radiopharmaceutical. The isotope [[technetium-99m]] (Tc-99m) is a metastable nuclear isomer used in various diagnostic imaging procedures. Tc-99m is obtained from a [[molybdenum-99]] generator, where it is eluted as sodium pertechnetate (NaTcO_).

	==~~See Also~~==		In medical imaging, Tc-99m pertechnetate is used for imaging the [[thyroid gland]], [[salivary glands]], and for [[brain imaging]] in certain cases. It is also used in [[renal imaging]] and to assess [[gastrointestinal bleeding]].
	* [[Technetium~~-99m~~]]
			== Chemistry ==
			In aqueous solution, pertechnetate is stable over a wide range of pH. It can be reduced to lower oxidation states of technetium, such as Tc(IV) and Tc(V), under reducing conditions. The reduction of pertechnetate is an important consideration in the management of [[radioactive waste]], as technetium can be a long-lived fission product in nuclear reactors.

			== Safety ==
			As a radioactive substance, pertechnetate must be handled with care to minimize exposure to radiation. In medical settings, the use of Tc-99m pertechnetate is carefully controlled to ensure patient and staff safety.

			== Related pages ==
			* [[Technetium]]
	* [[Nuclear medicine]]		* [[Nuclear medicine]]
	* [[Radiopharmaceutical]]		* [[Radiopharmaceutical]]
			* [[Technetium-99m]]
			* [[Radioactive waste management]]

	[[Category:~~Chemical~~ compounds]]		[[Category:Technetium compounds]]
			[[Category:Oxyanions]]
	[[Category:Nuclear medicine]]		[[Category:Nuclear medicine]]
	~~[[Category:Radiopharmaceuticals]]~~

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2024-02-25T22:17:10Z

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'''Pertechnetate''' is a [[chemical compound]] that is commonly used in [[nuclear medicine]] for diagnostic purposes. It is a [[technetium]] compound with the chemical formula TcO4−. Pertechnetate is a monovalent [[anion]] and is the most stable oxidation state of technetium. It is similar in chemical behavior to [[perchlorate]].

==Chemical Properties==
Pertechnetate is a strong [[oxidizing agent]]. It is soluble in water and its solutions are colorless. The compound is stable in air. It can be reduced to technetium by [[electrolysis]].

==Medical Uses==
In nuclear medicine, pertechnetate is used as a [[radiopharmaceutical]]. It is used in the diagnosis of several medical conditions, including [[thyroid disease]], [[heart disease]], and [[cancer]]. Pertechnetate is also used in the [[scintigraphy]] of the [[salivary gland]] and in the [[Meckel's diverticulum]] scan.

==Production==
Pertechnetate is produced by the [[oxidation]] of technetium-99m, a [[radioisotope]] of technetium. The oxidation is usually carried out in an [[alkaline solution]] using [[chloramine-T]] as the oxidizing agent.

==Safety==
As a radioactive compound, pertechnetate must be handled with care. It should be used only by trained professionals in a controlled environment. The compound is not suitable for use in patients who are pregnant or breastfeeding.

==See Also==
* [[Technetium-99m]]
* [[Nuclear medicine]]
* [[Radiopharmaceutical]]

[[Category:Chemical compounds]]
[[Category:Nuclear medicine]]
[[Category:Radiopharmaceuticals]]

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Pertechnetate - Revision history

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