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			{{SI}}
			{{Infobox medical condition
			\| name = Perforating calcific elastosis
			\| image = [[File:Histopathology_of_perforating_calcific_elastosis.jpg\|left\|thumb\|Histopathology of perforating calcific elastosis]]
			\| caption = Histopathological image showing features of perforating calcific elastosis
			\| synonyms =
			\| specialty = [[Dermatology]]
			\| symptoms = Skin lesions, [[pruritus]]
			\| complications =
			\| onset =
			\| duration =
			\| causes =
			\| risks =
			\| diagnosis = [[Skin biopsy]]
			\| differential = [[Pseudoxanthoma elasticum]], [[Elastosis perforans serpiginosa]]
			\| prevention =
			\| treatment =
			\| medication =
			\| prognosis =
			\| frequency =
			}}
	'''Perforating calcific elastosis''' is a rare skin condition characterized by the deposition of calcium in the skin's elastic fibers, leading to their perforation. It is often associated with kidney disease, particularly in patients undergoing dialysis.		'''Perforating calcific elastosis''' is a rare skin condition characterized by the deposition of calcium in the skin's elastic fibers, leading to their perforation. It is often associated with kidney disease, particularly in patients undergoing dialysis.

	== Symptoms ==		== Symptoms ==
	The primary symptom of perforating calcific elastosis is the appearance of small, white, firm papules on the skin. These papules are typically found on the extremities, particularly the hands and feet. They may be asymptomatic or cause mild itching.		The primary symptom of perforating calcific elastosis is the appearance of small, white, firm papules on the skin. These papules are typically found on the extremities, particularly the hands and feet. They may be asymptomatic or cause mild itching.

	== Causes ==		== Causes ==
	The exact cause of perforating calcific elastosis is unknown. However, it is often associated with chronic kidney disease and dialysis. The condition is thought to result from an imbalance in calcium and phosphate metabolism, leading to the deposition of calcium in the skin's elastic fibers.		The exact cause of perforating calcific elastosis is unknown. However, it is often associated with chronic kidney disease and dialysis. The condition is thought to result from an imbalance in calcium and phosphate metabolism, leading to the deposition of calcium in the skin's elastic fibers.

	== Diagnosis ==		== Diagnosis ==
	Diagnosis of perforating calcific elastosis is typically made through a skin biopsy. Under the microscope, the skin shows characteristic changes, including the presence of calcium deposits in the elastic fibers and their perforation.		Diagnosis of perforating calcific elastosis is typically made through a skin biopsy. Under the microscope, the skin shows characteristic changes, including the presence of calcium deposits in the elastic fibers and their perforation.

	== Treatment ==		== Treatment ==
	There is no specific treatment for perforating calcific elastosis. Management is primarily aimed at controlling the underlying kidney disease and maintaining a balance in calcium and phosphate levels. Topical steroids and emollients may be used to manage the skin symptoms.		There is no specific treatment for perforating calcific elastosis. Management is primarily aimed at controlling the underlying kidney disease and maintaining a balance in calcium and phosphate levels. Topical steroids and emollients may be used to manage the skin symptoms.

	== See also ==		== See also ==
	* [[Calciphylaxis]]		* [[Calciphylaxis]]
	* [[Chronic kidney disease]]		* [[Chronic kidney disease]]
	* [[Dialysis]]		* [[Dialysis]]

	[[Category:Skin conditions]]		[[Category:Skin conditions]]
	[[Category:Kidney diseases]]		[[Category:Kidney diseases]]

	{{stub}}		{{stub}}

	== References ==		== References ==
	<references />		<references />

	== External links ==		== External links ==
	* [https://www.ncbi.nlm.nih.gov/pubmed/17627897 Perforating calcific elastosis in a patient on chronic dialysis: a case report and review of the literature]		* [https://www.ncbi.nlm.nih.gov/pubmed/17627897 Perforating calcific elastosis in a patient on chronic dialysis: a case report and review of the literature]
	* [https://www.ncbi.nlm.nih.gov/pubmed/17627897 Perforating calcific elastosis: a review of the literature]		* [https://www.ncbi.nlm.nih.gov/pubmed/17627897 Perforating calcific elastosis: a review of the literature]

	{{Skin and connective tissue disease}}		{{Skin and connective tissue disease}}
	{{Kidney diseases}}		{{Kidney diseases}} {{stub}}
	{{~~dictionary-stub1~~}}
	~~<gallery>~~
	~~File:Histopathology_of_perforating_calcific_elastosis.jpg\|Histopathology of perforating calcific elastosis~~
	~~</gallery>~~

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	{{Kidney diseases}}		{{Kidney diseases}}
	{{dictionary-stub1}}		{{dictionary-stub1}}
			<gallery>
			File:Histopathology_of_perforating_calcific_elastosis.jpg\|Histopathology of perforating calcific elastosis
			</gallery>

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2024-02-24T23:18:14Z

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'''Perforating calcific elastosis''' is a rare skin condition characterized by the deposition of calcium in the skin's elastic fibers, leading to their perforation. It is often associated with kidney disease, particularly in patients undergoing dialysis.

== Symptoms ==
The primary symptom of perforating calcific elastosis is the appearance of small, white, firm papules on the skin. These papules are typically found on the extremities, particularly the hands and feet. They may be asymptomatic or cause mild itching.

== Causes ==
The exact cause of perforating calcific elastosis is unknown. However, it is often associated with chronic kidney disease and dialysis. The condition is thought to result from an imbalance in calcium and phosphate metabolism, leading to the deposition of calcium in the skin's elastic fibers.

== Diagnosis ==
Diagnosis of perforating calcific elastosis is typically made through a skin biopsy. Under the microscope, the skin shows characteristic changes, including the presence of calcium deposits in the elastic fibers and their perforation.

== Treatment ==
There is no specific treatment for perforating calcific elastosis. Management is primarily aimed at controlling the underlying kidney disease and maintaining a balance in calcium and phosphate levels. Topical steroids and emollients may be used to manage the skin symptoms.

== See also ==
* [[Calciphylaxis]]
* [[Chronic kidney disease]]
* [[Dialysis]]

[[Category:Skin conditions]]
[[Category:Kidney diseases]]

{{stub}}

== References ==
<references />

== External links ==
* [https://www.ncbi.nlm.nih.gov/pubmed/17627897 Perforating calcific elastosis in a patient on chronic dialysis: a case report and review of the literature]
* [https://www.ncbi.nlm.nih.gov/pubmed/17627897 Perforating calcific elastosis: a review of the literature]

{{Skin and connective tissue disease}}
{{Kidney diseases}}
{{dictionary-stub1}}

Perforating calcific elastosis - Revision history

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