https://wikimd.org/index.php?action=history&feed=atom&title=Pegylated_interferon Pegylated interferon - Revision history 2026-04-27T06:44:09Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=Pegylated_interferon&diff=6517469&oldid=prev Prab: CSV import 2025-03-17T22:52:41Z <p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 22:52, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l32">Line 32:</td> <td colspan="2" class="diff-lineno">Line 32:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; 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font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table> Prab https://wikimd.org/index.php?title=Pegylated_interferon&diff=5374697&oldid=prev Prab: CSV import 2024-03-08T18:26:07Z <p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;Pegylated interferon&#039;&#039;&#039; (&#039;&#039;&#039;PEG-IFN&#039;&#039;&#039;) is a form of [[interferon]] used in the treatment of [[chronic hepatitis C]] and [[hepatitis B]]. The medication is designed to be absorbed slowly, allowing for a longer duration of therapeutic effect. <br /> <br /> == Mechanism of Action ==<br /> Pegylated interferon works by stimulating the body&#039;s [[immune system]] to fight off viral infections. It binds to specific receptors on the surface of cells, triggering a cascade of immune responses that inhibit viral replication and promote the clearance of infected cells. <br /> <br /> == Pharmacokinetics ==<br /> The pegylation process, which involves the attachment of polyethylene glycol (PEG) to the interferon molecule, increases the size of the molecule and reduces its clearance from the body. This results in a longer half-life and allows for less frequent dosing compared to standard interferon.<br /> <br /> == Clinical Use ==<br /> Pegylated interferon is primarily used in the treatment of chronic hepatitis C and B. It is often used in combination with other antiviral drugs, such as [[ribavirin]], to increase the likelihood of achieving a sustained virologic response (SVR). <br /> <br /> == Side Effects ==<br /> Common side effects of pegylated interferon include flu-like symptoms, depression, fatigue, and hematologic abnormalities such as neutropenia and thrombocytopenia. Severe side effects can include autoimmune disorders, psychiatric symptoms, and cardiovascular or pulmonary complications.<br /> <br /> == Contraindications ==<br /> Pegylated interferon is contraindicated in patients with decompensated liver disease, autoimmune hepatitis, and in those with a history of severe psychiatric disorders. It should be used with caution in patients with cardiac disease.<br /> <br /> == See Also ==<br /> * [[Interferon]]<br /> * [[Hepatitis C]]<br /> * [[Hepatitis B]]<br /> * [[Ribavirin]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Antiviral drugs]]<br /> [[Category:Hepatitis C]]<br /> [[Category:Hepatitis B]]<br /> [[Category:Pharmacology]]<br /> <br /> {{pharmacology-stub}}</div> Prab