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	<id>https://wikimd.com/index.php?action=history&amp;feed=atom&amp;title=PRKAR1A</id>
	<title>PRKAR1A - Revision history</title>
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	<updated>2026-04-22T08:07:12Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.com/index.php?title=PRKAR1A&amp;diff=6516275&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=PRKAR1A&amp;diff=6516275&amp;oldid=prev"/>
		<updated>2025-03-17T21:35:40Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 21:35, 17 March 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l29&quot;&gt;Line 29:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=PRKAR1A&amp;diff=6268198&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=PRKAR1A&amp;diff=6268198&amp;oldid=prev"/>
		<updated>2025-02-11T01:23:46Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 01:23, 11 February 2025&lt;/td&gt;
				&lt;/tr&gt;&lt;tr&gt;&lt;td colspan=&quot;2&quot; class=&quot;diff-lineno&quot; id=&quot;mw-diff-left-l28&quot;&gt;Line 28:&lt;/td&gt;
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&lt;/table&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=PRKAR1A&amp;diff=5330420&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=PRKAR1A&amp;diff=5330420&amp;oldid=prev"/>
		<updated>2024-02-29T04:05:27Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;PRKAR1A&amp;#039;&amp;#039;&amp;#039; is a gene that provides instructions for making one of the four subunits of the protein kinase A (PKA) enzyme. This enzyme plays a key role in a process known as signal transduction, which transmits signals from outside the cell to the cell&amp;#039;s nucleus. &lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
&lt;br /&gt;
The [[PRKAR1A]] gene encodes the regulatory subunit type I-alpha of the cAMP-dependent protein kinase, which is involved in the regulation of cellular functions such as differentiation, proliferation, and apoptosis. Mutations in this gene have been associated with [[Carney complex]], [[acrodysostosis]], and other diseases.&lt;br /&gt;
&lt;br /&gt;
== Structure ==&lt;br /&gt;
&lt;br /&gt;
The PRKAR1A gene is located on the short (p) arm of chromosome 17 at position 22.2. More precisely, the PRKAR1A gene is located from base pair 57,278,406 to base pair 57,294,358 on chromosome 17.&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
&lt;br /&gt;
Mutations in the PRKAR1A gene have been associated with [[Carney complex]], a rare condition characterized by spotty skin pigmentation, heart tumors, and endocrine abnormalities. Mutations in this gene can also cause isolated [[acrodysostosis]], a rare skeletal disorder characterized by short stature and distinctive facial features.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Protein kinase A]]&lt;br /&gt;
* [[Carney complex]]&lt;br /&gt;
* [[Acrodysostosis]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* [https://www.ncbi.nlm.nih.gov/gene/5573 PRKAR1A] at NCBI&lt;br /&gt;
* [https://ghr.nlm.nih.gov/gene/PRKAR1A PRKAR1A] at Genetics Home Reference&lt;br /&gt;
&lt;br /&gt;
[[Category:Genes]]&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
{{genetics-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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