https://wikimd.org/index.php?action=history&feed=atom&title=POU4F3 2026-05-11T14:27:39Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=POU4F3&diff=6516138&oldid=prev 2025-03-17T21:26:37Z

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Prab https://wikimd.org/index.php?title=POU4F3&diff=6274970&oldid=prev 2025-02-11T04:15:13Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:15, 11 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l24">Line 24:</td> <td colspan="2" class="diff-lineno">Line 24:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{gene-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{gene-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=POU4F3&diff=5328972&oldid=prev 2024-02-29T02:44:00Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;POU4F3&#039;&#039;&#039; is a gene that encodes a member of the POU-domain family of transcription factors. POU-domain proteins have been observed to play important roles in control of cell identity in several systems. A class IV POU-domain protein, POU4F3 is involved in neurogenesis and development of the auditory system. Mutations in this gene have been associated with [[hearing loss]].<br /> <br /> == Function ==<br /> The POU4F3 gene provides instructions for making a protein that is found in the inner ear. This protein is a transcription factor, which means it attaches (binds) to specific regions of DNA and helps control the activity of certain genes. Researchers believe that the POU4F3 protein is involved in the development and maintenance of hair cells, which are the sensory cells of the inner ear that are essential for normal hearing.<br /> <br /> == Clinical significance ==<br /> Mutations in the POU4F3 gene are associated with autosomal dominant non-syndromic sensorineural type 15 deafness (DFNA15). DFNA15 is a form of [[genetic deafness]]. If a mutation occurs in the POU4F3 gene, the resulting protein may not bind to DNA effectively. This can disrupt the normal development and maintenance of hair cells, leading to their degeneration and resulting in progressive hearing loss.<br /> <br /> == Research ==<br /> Research into the POU4F3 gene and its associated protein may lead to new treatments for hearing loss. Understanding the role of this gene in the development and maintenance of hair cells could provide insights into the causes of genetic deafness and potentially lead to strategies for preventing or treating this condition.<br /> <br /> == See also ==<br /> * [[POU domain]]<br /> * [[Transcription factor]]<br /> * [[Hearing loss]]<br /> * [[Genetic deafness]]<br /> <br /> == References ==<br /> &lt;references /&gt;<br /> <br /> [[Category:Genes]]<br /> [[Category:Hearing]]<br /> [[Category:Deafness]]<br /> {{gene-stub}}<br /> {{medicine-stub}}</div>

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