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	<title>PITX1 - Revision history</title>
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	<updated>2026-04-23T21:59:06Z</updated>
	<subtitle>Revision history for this page on the wiki</subtitle>
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	<entry>
		<id>https://wikimd.com/index.php?title=PITX1&amp;diff=6516341&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=PITX1&amp;diff=6516341&amp;oldid=prev"/>
		<updated>2025-03-17T21:40:00Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 21:40, 17 March 2025&lt;/td&gt;
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		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=PITX1&amp;diff=6257863&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=PITX1&amp;diff=6257863&amp;oldid=prev"/>
		<updated>2025-02-10T20:43:28Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;table style=&quot;background-color: #fff; color: #202122;&quot; data-mw=&quot;interface&quot;&gt;
				&lt;col class=&quot;diff-marker&quot; /&gt;
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				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;← Older revision&lt;/td&gt;
				&lt;td colspan=&quot;2&quot; style=&quot;background-color: #fff; color: #202122; text-align: center;&quot;&gt;Revision as of 20:43, 10 February 2025&lt;/td&gt;
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		<author><name>Prab</name></author>
	</entry>
	<entry>
		<id>https://wikimd.com/index.php?title=PITX1&amp;diff=5379404&amp;oldid=prev</id>
		<title>Prab: CSV import</title>
		<link rel="alternate" type="text/html" href="https://wikimd.com/index.php?title=PITX1&amp;diff=5379404&amp;oldid=prev"/>
		<updated>2024-03-10T06:22:38Z</updated>

		<summary type="html">&lt;p&gt;CSV import&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;PITX1&amp;#039;&amp;#039;&amp;#039; is a protein that in humans is encoded by the PITX1 gene. It is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression, playing a role in [[osteogenesis]] and [[bone development]].&lt;br /&gt;
&lt;br /&gt;
== Function ==&lt;br /&gt;
PITX1 is a transcription factor that plays a crucial role in the development of several tissues, including [[hindlimb]], [[craniofacial muscles]], [[pituitary gland]], and [[larynx]]. It is involved in the transcriptional activation of specific genes during cellular differentiation and development.&lt;br /&gt;
&lt;br /&gt;
== Clinical significance ==&lt;br /&gt;
Mutations in the PITX1 gene are associated with [[Liebenberg syndrome]], a rare disorder characterized by the transformation of forearm muscles into ones normally found in the lower leg. This condition is also known as &amp;quot;arm to leg transformation&amp;quot;. &lt;br /&gt;
&lt;br /&gt;
== Genetics ==&lt;br /&gt;
The PITX1 gene is located on the short (p) arm of chromosome 5 at position 31.1. More precisely, the PITX1 gene is located from base pair 133,591,065 to base pair 133,617,839 on chromosome 5.&lt;br /&gt;
&lt;br /&gt;
== See also ==&lt;br /&gt;
* [[Homeobox]]&lt;br /&gt;
* [[Transcription factor]]&lt;br /&gt;
* [[Liebenberg syndrome]]&lt;br /&gt;
&lt;br /&gt;
== References ==&lt;br /&gt;
&amp;lt;references /&amp;gt;&lt;br /&gt;
&lt;br /&gt;
== External links ==&lt;br /&gt;
* [https://www.ncbi.nlm.nih.gov/gene/5307 NCBI Gene]&lt;br /&gt;
* [https://ghr.nlm.nih.gov/gene/PITX1 Genetics Home Reference]&lt;br /&gt;
&lt;br /&gt;
[[Category:Transcription factors]]&lt;br /&gt;
[[Category:Human proteins]]&lt;br /&gt;
[[Category:Genes on human chromosome 5]]&lt;br /&gt;
&lt;br /&gt;
{{medicine-stub}}&lt;/div&gt;</summary>
		<author><name>Prab</name></author>
	</entry>
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