https://wikimd.org/index.php?action=history&feed=atom&title=PDX1 2026-04-26T07:21:23Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=PDX1&diff=6516579&oldid=prev 2025-03-17T21:56:30Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 21:56, 17 March 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l29">Line 29:</td> <td colspan="2" class="diff-lineno">Line 29:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{No image}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">__NOINDEX__</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=PDX1&diff=6252268&oldid=prev 2025-02-10T20:21:30Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 20:21, 10 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l28">Line 28:</td> <td colspan="2" class="diff-lineno">Line 28:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biology-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{biology-stub}}</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{medicine-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">{{No image}}</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=PDX1&diff=5331642&oldid=prev 2024-02-29T05:16:46Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;PDX1‏‎&#039;&#039;&#039; (Pancreatic and duodenal homeobox 1) is a [[transcription factor]] that plays a crucial role in [[pancreas]] development and the maintenance of normal [[pancreatic]] functions in adults. It is encoded by the &#039;&#039;PDX1&#039;&#039; gene in humans.<br /> <br /> == Function ==<br /> <br /> PDX1 is a transcription factor that regulates the expression of several genes involved in pancreatic development and function. It is essential for the development of the pancreas and is also involved in the differentiation of [[pancreatic beta cells]], which produce [[insulin]]. In adults, PDX1 continues to regulate the function of pancreatic beta cells and is necessary for normal insulin secretion.<br /> <br /> == Clinical significance ==<br /> <br /> Mutations in the &#039;&#039;PDX1&#039;&#039; gene can lead to pancreatic agenesis, a rare condition in which the pancreas fails to develop. This results in permanent [[neonatal diabetes mellitus]]. Mutations in &#039;&#039;PDX1&#039;&#039; can also cause [[MODY]] (Maturity Onset Diabetes of the Young), a form of diabetes that typically develops in adolescence or early adulthood.<br /> <br /> In addition, reduced expression of PDX1 has been observed in type 2 diabetes, suggesting that it may also play a role in this more common form of diabetes.<br /> <br /> == Research ==<br /> <br /> Research into PDX1 has provided valuable insights into the development of the pancreas and the pathogenesis of diabetes. It has also led to the development of new therapeutic strategies for diabetes, such as the use of PDX1-expressing stem cells to replace damaged or lost beta cells.<br /> <br /> == See also ==<br /> <br /> * [[Transcription factor]]<br /> * [[Pancreas]]<br /> * [[Insulin]]<br /> * [[Diabetes mellitus]]<br /> * [[MODY]]<br /> <br /> [[Category:Transcription factors]]<br /> [[Category:Pancreas]]<br /> [[Category:Diabetes]]<br /> {{biology-stub}}<br /> {{medicine-stub}}</div>

Prab