https://wikimd.org/index.php?action=history&feed=atom&title=PDE3_inhibitor 2026-04-27T12:53:22Z Revision history for this page on the wiki MediaWiki 1.44.2 https://wikimd.org/index.php?title=PDE3_inhibitor&diff=6317240&oldid=prev 2025-02-18T04:30:26Z

<p>CSV import</p> <table style="background-color: #fff; color: #202122;" data-mw="interface"> <col class="diff-marker" /> <col class="diff-content" /> <col class="diff-marker" /> <col class="diff-content" /> <tr class="diff-title" lang="en"> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">← Older revision</td> <td colspan="2" style="background-color: #fff; color: #202122; text-align: center;">Revision as of 04:30, 18 February 2025</td> </tr><tr><td colspan="2" class="diff-lineno" id="mw-diff-left-l24">Line 24:</td> <td colspan="2" class="diff-lineno">Line 24:</td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Pharmacology]]</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>[[Category:Pharmacology]]</div></td></tr> <tr><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Pharmacology-stub}}</div></td><td class="diff-marker"></td><td style="background-color: #f8f9fa; color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #eaecf0; vertical-align: top; white-space: pre-wrap;"><div>{{Pharmacology-stub}}</div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">== PDE3_inhibitor ==</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;gallery&gt;</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Milrinone.svg|Milrinone chemical structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:CI-930_HPI_pattern.svg|CI-930 HPI pattern</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Theophyllin_-_Theophylline.svg|Theophylline chemical structure</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:Meribendan_skeletal.svg|Meribendan skeletal formula</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">File:CI-930_skeletal.svg|CI-930 skeletal formula</ins></div></td></tr> <tr><td colspan="2" class="diff-side-deleted"></td><td class="diff-marker" data-marker="+"></td><td style="color: #202122; font-size: 88%; border-style: solid; border-width: 1px 1px 1px 4px; border-radius: 0.33em; border-color: #a3d3ff; vertical-align: top; white-space: pre-wrap;"><div><ins style="font-weight: bold; text-decoration: none;">&lt;/gallery&gt;</ins></div></td></tr> </table>

Prab https://wikimd.org/index.php?title=PDE3_inhibitor&diff=5329554&oldid=prev 2024-02-29T03:17:13Z

<p>CSV import</p> <p><b>New page</b></p><div>&#039;&#039;&#039;PDE3 inhibitor&#039;&#039;&#039; is a type of [[drug]] that inhibits the action of [[phosphodiesterase 3]] (PDE3), an enzyme found in the heart and blood vessels. PDE3 inhibitors are used in the treatment of [[heart failure]] and other cardiovascular conditions.<br /> <br /> == Mechanism of action ==<br /> PDE3 inhibitors work by blocking the action of PDE3, an enzyme that breaks down [[cyclic adenosine monophosphate]] (cAMP) in the heart and blood vessels. By inhibiting PDE3, these drugs increase the levels of cAMP, which in turn enhances the contractility of the heart muscle and causes vasodilation. This results in improved heart function and increased blood flow.<br /> <br /> == Uses ==<br /> PDE3 inhibitors are used in the treatment of heart failure, a condition in which the heart is unable to pump enough blood to meet the body&#039;s needs. They are also used to treat certain types of [[arrhythmia]], or irregular heartbeat.<br /> <br /> In addition, PDE3 inhibitors are used in the management of [[pulmonary hypertension]], a condition characterized by high blood pressure in the arteries of the lungs. By causing vasodilation, these drugs can help to reduce the pressure in these arteries and improve symptoms.<br /> <br /> == Examples ==<br /> Examples of PDE3 inhibitors include [[milrinone]], [[cilostazol]], and [[enoximone]]. Milrinone and enoximone are typically used in the treatment of heart failure, while cilostazol is used to treat [[intermittent claudication]], a condition characterized by pain in the legs due to inadequate blood flow.<br /> <br /> == Side effects ==<br /> Like all drugs, PDE3 inhibitors can cause side effects. These may include [[nausea]], [[vomiting]], [[headache]], and [[arrhythmia]]. In rare cases, PDE3 inhibitors can cause severe cardiovascular side effects, such as [[cardiac arrest]] or [[stroke]].<br /> <br /> == See also ==<br /> * [[Phosphodiesterase inhibitor]]<br /> * [[Heart failure]]<br /> * [[Pulmonary hypertension]]<br /> <br /> [[Category:Drugs]]<br /> [[Category:Cardiovascular drugs]]<br /> [[Category:Pharmacology]]<br /> {{Pharmacology-stub}}</div>

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