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	== PDBe-KB ==		== PDBe-KB ==
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			== PDBe-KB ==
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{{Infobox database
| name = PDBe-KB
| logo = 
| description = A community-driven resource for structural and functional annotations of proteins.
| url = [https://pdbe-kb.org/ PDBe-KB]
| commercial = No
| type = Biological database
| registration = Optional
| owner = European Bioinformatics Institute (EMBL-EBI)
| launch date = 2019
}}

'''PDBe-KB''' (Protein Data Bank in Europe - Knowledge Base) is a collaborative resource that integrates structural and functional annotations of proteins. It is part of the [[Protein Data Bank in Europe]] (PDBe) and is hosted by the [[European Bioinformatics Institute]] (EMBL-EBI). PDBe-KB aims to provide a comprehensive view of protein structures by aggregating data from various sources, including experimental data, computational predictions, and community annotations.

==Overview==
PDBe-KB was established to address the need for a centralized platform that combines structural data with functional annotations. The resource is designed to facilitate the understanding of protein function in the context of their three-dimensional structures. It serves as a hub for researchers, educators, and students in the field of structural biology and bioinformatics.

==Features==
PDBe-KB offers several features that enhance the usability and accessibility of protein structural data:

* '''Integrated Annotations''': PDBe-KB aggregates annotations from multiple sources, including experimental data from the [[Protein Data Bank]] (PDB), computational predictions, and community contributions.

* '''Functional Annotations''': The platform provides detailed functional annotations, such as ligand binding sites, protein-protein interactions, and post-translational modifications.

* '''Visualization Tools''': Users can visualize protein structures and their annotations using interactive 3D viewers, which are integrated into the PDBe-KB interface.

* '''Search and Retrieval''': PDBe-KB offers advanced search capabilities, allowing users to query the database using various criteria, such as protein name, PDB ID, or functional annotation.

==Community Involvement==
PDBe-KB is a community-driven resource, encouraging contributions from researchers and experts in the field. The platform supports the submission of new annotations and the curation of existing data, fostering a collaborative environment for the continuous improvement of the resource.

==Applications==
PDBe-KB is widely used in research and education. It supports:

* '''Structural Biology Research''': By providing comprehensive structural and functional data, PDBe-KB aids researchers in understanding protein mechanisms and interactions.

* '''Drug Discovery''': The detailed annotations of ligand binding sites and protein interactions are valuable for drug design and discovery efforts.

* '''Education''': PDBe-KB serves as an educational tool for teaching structural biology and bioinformatics, offering students access to a wealth of annotated protein structures.

==Also see==
* [[Protein Data Bank]]
* [[European Bioinformatics Institute]]
* [[Structural Biology]]
* [[Bioinformatics]]
* [[Protein Structure]]

==External links==
* [https://pdbe-kb.org/ Official PDBe-KB website]

{{Protein databases}}
{{Bioinformatics}}

[[Category:Biological databases]]
[[Category:Bioinformatics]]
[[Category:Protein structure]]

PDBe-KB - Revision history

Prab at 00:56, 17 March 2025

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