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	'''OR4Q3''' is a gene that encodes the olfactory receptor, family ~~4, subfamily Q, member 3 in humans~~. ~~The [[olfactory receptor]] proteins~~ are ~~members of a large family~~ of G-protein coupled receptors (GPCR) ~~arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and~~ are responsible for the ~~recognition and G protein-mediated transduction~~ of ~~odorant signals. The olfactory receptor gene family is the largest in the genome~~.		OR4Q3

			'''OR4Q3''' is a gene that encodes a member of the olfactory receptor family of proteins. These receptors are part of the G-protein-coupled receptors (GPCR) superfamily, which are responsible for detecting odor molecules and initiating a neuronal response that triggers the perception of smell.

	== Function ==		== Function ==
			Olfactory receptors, such as OR4Q3, are expressed in the olfactory epithelium and are involved in the detection of odorants. Each olfactory receptor is capable of binding to a specific set of odor molecules, which allows for the discrimination of a wide variety of smells. The binding of an odorant to an olfactory receptor activates a G-protein-mediated signal transduction pathway, leading to a neuronal response.
	~~The~~ OR4Q3 ~~gene is part~~ of ~~the [[~~olfactory receptor~~]] gene family~~, which is the ~~largest gene family in the human genome~~. The ~~proteins encoded by these genes are responsible for the recognition and transduction~~ of odorant ~~signals, which are mediated by G proteins.~~

	~~[[File:Olfactory receptors.jpg\|thumb\|right\|Olfactory receptors are responsible for the recognition and~~ G protein-mediated transduction ~~of odorant signals~~.]]

	== Structure ==		== Structure ==
			Olfactory receptors, including OR4Q3, share a common structure characterized by seven transmembrane domains. This structure is typical of many [[G-protein-coupled receptors]], which are involved in various physiological processes beyond olfaction.

	The OR4Q3 gene is located on chromosome ~~14q11~~.~~1 and~~ is ~~composed~~ of a ~~single coding exon~~. The ~~protein encoded by this gene shares~~ a ~~7-transmembrane domain structure with many neurotransmitter and hormone receptors~~.		== Genetic Information ==
			The '''OR4Q3''' gene is located on [[chromosome 11]] in humans. It is part of a large family of olfactory receptor genes, which are the largest gene family in the human genome. The diversity of these genes allows for the detection of a vast array of odorant molecules.

	== Clinical Significance ==		== Clinical Significance ==
			While the primary function of OR4Q3 is related to the sense of smell, variations in olfactory receptor genes can have broader implications. For example, changes in olfactory function can be an early indicator of [[neurodegenerative diseases]] such as [[Parkinson's disease]] and [[Alzheimer's disease]].
	While the ~~specific clinical significance~~ of OR4Q3 is ~~not yet fully understood~~, olfactory ~~receptors in general~~ have ~~been implicated~~ in ~~a variety~~ of ~~diseases and conditions, including~~ [[~~anosmia~~]] ~~(loss of smell), and neurodegenerative diseases~~ such as [[Parkinson's disease]] and [[Alzheimer's disease]].

	== Research ==		== Research ==
			Research into olfactory receptors like OR4Q3 continues to provide insights into the molecular mechanisms of smell and its impact on human health. Understanding these receptors can also contribute to the development of artificial sensing devices and novel therapeutic approaches.
	Research into the ~~OR4Q3 gene~~ and its ~~encoded protein is ongoing, with scientists seeking~~ to ~~better understand its function~~ and ~~potential role in disease~~.

	== See Also ==		== See Also ==

	* [[Olfactory receptor]]		* [[Olfactory receptor]]
	* [[G protein-coupled receptor]]		* [[G-protein-coupled receptor]]
	* [[~~Anosmia]]~~		* [[Chromosome 11]]
	* [[Parkinson's disease]]
	* [[Alzheimer's disease]]

	== References ==		== References ==
			<references/>

			== External Links ==
			* [Olfactory Receptor Database](http://www.olfactory-receptor.org/)

	{{~~Reflist~~}}		{{Olfactory receptors}}

	[[Category:~~Genes~~]]		[[Category:Olfactory receptors]]
			[[Category:G-protein coupled receptors]]
	[[Category:Human proteins]]		[[Category:Human proteins]]
	[[Category:~~Olfactory system~~]]		[[Category:Genes on human chromosome 11]]
	~~[[Category:G protein-coupled receptors]]~~

	~~{{gene-stub}}~~
	~~{{medicine-stub}}~~

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2024-03-10T06:06:52Z

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'''OR4Q3''' is a gene that encodes the olfactory receptor, family 4, subfamily Q, member 3 in humans. The [[olfactory receptor]] proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

== Function ==

The OR4Q3 gene is part of the [[olfactory receptor]] gene family, which is the largest gene family in the human genome. The proteins encoded by these genes are responsible for the recognition and transduction of odorant signals, which are mediated by G proteins.

[[File:Olfactory receptors.jpg|thumb|right|Olfactory receptors are responsible for the recognition and G protein-mediated transduction of odorant signals.]]

== Structure ==

The OR4Q3 gene is located on chromosome 14q11.1 and is composed of a single coding exon. The protein encoded by this gene shares a 7-transmembrane domain structure with many neurotransmitter and hormone receptors.

== Clinical Significance ==

While the specific clinical significance of OR4Q3 is not yet fully understood, olfactory receptors in general have been implicated in a variety of diseases and conditions, including [[anosmia]] (loss of smell), and neurodegenerative diseases such as [[Parkinson's disease]] and [[Alzheimer's disease]].

== Research ==

Research into the OR4Q3 gene and its encoded protein is ongoing, with scientists seeking to better understand its function and potential role in disease.

== See Also ==

* [[Olfactory receptor]]
* [[G protein-coupled receptor]]
* [[Anosmia]]
* [[Parkinson's disease]]
* [[Alzheimer's disease]]

== References ==

{{Reflist}}

[[Category:Genes]]
[[Category:Human proteins]]
[[Category:Olfactory system]]
[[Category:G protein-coupled receptors]]

{{gene-stub}}
{{medicine-stub}}

OR4Q3 - Revision history

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