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	'''OR2S2''' is a gene that encodes the olfactory receptor, family 2, subfamily S, member 2 protein in humans. The [[olfactory receptor]] proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

	== ~~Function~~ ==		{{Infobox gene
			\| name = OR2S2
			\| symbol = OR2S2
			\| HGNCid = 15000
			\| chromosome = 1
			\| arm = q
			\| band = 44.2
			}}

	~~The protein encoded by the~~ OR2S2 gene ~~is an [[~~olfactory receptor~~]], a type~~ of ~~G protein-coupled receptor that is~~ involved in the detection of ~~smell. Olfactory receptors interact with odorant~~ molecules ~~in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins~~ are ~~members of~~ a ~~large family~~ of G-protein coupled ~~receptors~~ (GPCR) ~~arising from single coding-exon genes~~.		'''OR2S2''' is a gene that encodes a member of the olfactory receptor family of proteins. These receptors are involved in the detection of odor molecules and are a part of the G-protein-coupled receptor (GPCR) superfamily.

	== ~~Gene~~ ==		==Function==
			Olfactory receptors, such as those encoded by the '''[[OR2S2]]''' gene, are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor proteins are characterized by a 7-transmembrane domain structure, which is also shared by many neurotransmitter and hormone receptors.

	The ~~OR2S2~~ gene is ~~located on~~ the ~~long (q) arm of [[chromosome 11]] at position 15~~.~~4. More precisely, the~~ OR2S2 gene is ~~located from base pair 34~~,~~378,879~~ to ~~base pair 34,380,062 on chromosome 11~~.		==Gene Family==
			The olfactory receptor gene family is the largest in the human genome. The '''OR2S2''' gene is one of many that contribute to the diversity of olfactory receptors, allowing humans to detect a wide range of smells.

	== ~~Clinical significance~~ ==		==Location==
			The '''OR2S2''' gene is located on the long arm (q) of [[chromosome 1]], specifically at band 44.2. This location is part of a cluster of olfactory receptor genes.

	While the ~~specific~~ function ~~and clinical significance~~ of OR2S2 is ~~not yet fully understood, olfactory receptors in general are known~~ to ~~play a role in a wide range of physiological processes. They are involved in the detection of smell~~, ~~but also in various other functions such as the regulation of [[appetite]] and [[metabolism]], and the detection of environmental hazards. Mutations~~ in olfactory receptor genes ~~have been~~ associated with ~~various diseases~~, ~~including [[congenital anosmia]] (inability~~ to ~~smell), [[obesity]], and certain types of [[cancer]]~~.		==Clinical Significance==
			While the primary function of '''OR2S2''' is related to olfaction, variations in olfactory receptor genes can sometimes be associated with differences in smell perception among individuals. However, specific clinical conditions directly linked to '''OR2S2''' have not been extensively documented.

	~~[[File:~~OR2S2 ~~gene location on human chromosome 11~~.~~png\|thumb\|right\|300px\|Location~~ of ~~the OR2S2 gene~~ on ~~chromosome 11~~.]]		==Research==
			Research into olfactory receptors like '''OR2S2''' continues to explore their role in the sensory system and potential implications in other physiological processes. Understanding these receptors can provide insights into the mechanisms of smell and its impact on behavior and health.
	~~== See also ==~~

			==See Also==
	* [[Olfactory receptor]]		* [[Olfactory receptor]]
	* [[G protein-coupled receptor]]		* [[G-protein-coupled receptor]]
	* [[Chromosome ~~11 (human)~~]]		* [[Chromosome 1]]

	== References ==		==References==
			{{Reflist}}

	~~{{Reflist}}~~		==External Links==
			* [https://www.ncbi.nlm.nih.gov/gene/OR2S2 NCBI Gene: OR2S2]
			* [https://www.genecards.org/cgi-bin/carddisp.pl?gene=OR2S2 GeneCards: OR2S2]

	[[Category:Genes on human chromosome 11]]		[[Category:Genes on human chromosome 1]]
	[[Category:Olfactory receptors]]		[[Category:Olfactory receptors]]
	[[Category:G protein-coupled receptors]]		[[Category:G protein-coupled receptors]]

	~~{{medicine-stub}}~~

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2024-03-10T06:12:56Z

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'''OR2S2''' is a gene that encodes the olfactory receptor, family 2, subfamily S, member 2 protein in humans. The [[olfactory receptor]] proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

== Function ==

The protein encoded by the OR2S2 gene is an [[olfactory receptor]], a type of G protein-coupled receptor that is involved in the detection of smell. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.

== Gene ==

The OR2S2 gene is located on the long (q) arm of [[chromosome 11]] at position 15.4. More precisely, the OR2S2 gene is located from base pair 34,378,879 to base pair 34,380,062 on chromosome 11.

== Clinical significance ==

While the specific function and clinical significance of OR2S2 is not yet fully understood, olfactory receptors in general are known to play a role in a wide range of physiological processes. They are involved in the detection of smell, but also in various other functions such as the regulation of [[appetite]] and [[metabolism]], and the detection of environmental hazards. Mutations in olfactory receptor genes have been associated with various diseases, including [[congenital anosmia]] (inability to smell), [[obesity]], and certain types of [[cancer]].

[[File:OR2S2 gene location on human chromosome 11.png|thumb|right|300px|Location of the OR2S2 gene on chromosome 11.]]

== See also ==

* [[Olfactory receptor]]
* [[G protein-coupled receptor]]
* [[Chromosome 11 (human)]]

== References ==

{{Reflist}}

[[Category:Genes on human chromosome 11]]
[[Category:Olfactory receptors]]
[[Category:G protein-coupled receptors]]

{{medicine-stub}}

OR2S2 - Revision history

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